Febrile cholestatic disease as an initial presentation of nodular lymphocyte-predominant Hodgkin lymphoma

Scientific paper - Original scientific paper

• Author: Anna Mrzljak
• Author: Slavko Gašparov
• Author: Ika Kardum-Skelin
• Author: Vesna Čolić-Cvrlje
• Author: Slobodanka Ostojić-Kolonić
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Febrile cholestatic liver disease is an extremely unusual presentation of Hodgkin lymphoma (HL). The liver biopsy of a 40-year-old man with febrile episodes and cholestatic laboratory pattern disclosed an uncommon subtype of HL, a nodular lymphocyte-predominant HL (NLPHL). Liver involvement in the early stage of the usually indolent NLPHL's clinical course suggests an aggressiveness and unfavorable outcome. Emphasizing a liver biopsy early in the diagnostic algorithm enables accurate diagnosis and appropriate treatment. Although rare, HL should be considered in the differential diagnosis of cholestasis.

• Keywords (english): Adult; Cholestasis / etiology; Cholestasis / physiopathology; Fatal Outcome; Fever / etiology; Fever / physiopathology; Hodgkin Disease / complications; Hodgkin Disease / diagnosis; Hodgkin Disease / pathology; Hodgkin Disease / physiopathology; Humans; Lymphocytes / pathology; Male
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: World Journal of Gastroenterology
• Numbering: vol. 16, no. 35, pp. 4491-4493
• p-ISSN: 1007-9327
• DOI: https://doi.org/10.3748/wjg.v16.i35.4491
• URN:NBN: urn:nbn:hr:105:289570
• Publication: 2010-09-21
• Document URL: https://doi.org/10.3748/wjg.v16.i35.4491
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 11:50:37