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Scientific paper - Review paper
The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients
Biomedicines, 11 (2023), 11; 3096. https://doi.org/10.3390/biomedicines11113096
Paklar, Nataša; Mijić, Maja; Filipec-Kanižaj, Tajana

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Paklar, N., Mijić, M. & Filipec Kanižaj, T. (2023). The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients. Biomedicines, 11. (11). doi: 10.3390/biomedicines11113096

Paklar, Nataša, et al. "The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients." Biomedicines, vol. 11, no. 11, 2023. https://doi.org/10.3390/biomedicines11113096

Paklar, Nataša, Maja Mijić and Tajana Filipec Kanižaj. "The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients." Biomedicines 11, no. 11 (2023). https://doi.org/10.3390/biomedicines11113096

Paklar, N., Mijić, M. and Filipec Kanižaj, T. (2023) 'The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients', Biomedicines, 11(11). doi: 10.3390/biomedicines11113096

Paklar N, Mijić M, Filipec Kanižaj T. The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients. Biomedicines [Internet]. 2023 November 20 [cited 2024 December 03];11(11). doi: 10.3390/biomedicines11113096

N. Paklar, M. Mijić and T. Filipec Kanižaj, "The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients", Biomedicines, vol. 11, no. 11, November 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:655015. [Accessed: 03 December 2024]

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Metadata
Title (english)The Outcomes of Liver Transplantation in Severe Metabolic Dysfunction-Associated Steatotic Liver Disease Patients
AuthorNataša Paklar
AuthorMaja Mijić
AuthorTajana Filipec-Kanižaj
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The increasing prevalence of diabetes mellitus, obesity, and metabolic syndrome in the population can lead to metabolic dysfunction-associated steatohepatitis (MASH) and metabolic dysfunction-associated steatotic liver disease (MASLD). In Western industrialized countries, this has become a major problem with significant socioeconomic impacts. MASH is now a leading cause of liver transplantation (LT), especially in developed countries. However, the post-transplant outcomes of such patients are a major concern, and published data are limited and extremely variable. In this article, we discuss graft and patient survival after LT, complications, the recurrence of MASH, and MASH appearing de novo after transplantation. Recent studies suggest that patients with MASH have slightly worse short-term survival, potentially due to increased cardiovascular mortality. However, most studies found that longer-term outcomes for patients undergoing LT for MASH are similar or even better than those for other indications. Hepatocellular carcinoma due to MASH cirrhosis also has similar or even better outcomes after LT than other etiologies. In conclusion, we suggest questions and topics that require further research to enhance healthcare for this growing patient population.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBiomedicines
Numberingvol. 11, no. 11, 3096
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines11113096
URN:NBNurn:nbn:hr:105:655015
Publication2023-11-20
Document URLhttps://www.mdpi.com/2227-9059/11/11/3096
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) icon
Created on2024-04-12 09:19:33