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SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia
Pathogens, 10 (2021), 6; 774. https://doi.org/10.3390/pathogens10060774
Vilibić-Čavlek, Tatjana; Stevanovic, Vladimir; Ilić, Maja; Barbić, Ljubo; Capak, Krunoslav; Tabain, Irena; Lenicek Krleza, Jasna; Ferenc, Thomas; Hruskar, Zeljka; Zrinski Topić, Renata; Kaliterna, Vanja; Antolović-Požgain, Arlen; Kučinar, Jasmina; Koščak, Iva; Mayer, Dijana; Sviben, Mario; Antolasic, Ljiljana; Milasincic, Ljiljana; Bucić, Lovro; Ferenčak, Ivana; Kaić, Bernard Više autora...

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Vilibić Čavlek, T., Stevanovic, V., Ilić, M., Barbić, Lj., Capak, K., Tabain, I. ... Kaić, B. (2021). SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia. Pathogens, 10. (6). doi: 10.3390/pathogens10060774

Vilibić Čavlek, Tatjana, et al. "SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia." Pathogens, vol. 10, br. 6, 2021. https://doi.org/10.3390/pathogens10060774

Vilibić Čavlek, Tatjana, Vladimir Stevanovic, Maja Ilić, Ljubo Barbić, Krunoslav Capak, Irena Tabain, Jasna Lenicek Krleza, et al. "SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia." Pathogens 10, br. 6 (2021). https://doi.org/10.3390/pathogens10060774

Vilibić Čavlek, T., et al. (2021) 'SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia', Pathogens, 10(6). doi: 10.3390/pathogens10060774

Vilibić Čavlek T, Stevanovic V, Ilić M, Barbić Lj, Capak K, Tabain I, i sur.. SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia. Pathogens [Internet]. 20.06.2021. [pristupljeno 20.04.2024.];10(6). doi: 10.3390/pathogens10060774

T. Vilibić Čavlek, et al., "SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia", Pathogens, vol. 10, br. 6, Lipanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:022605. [Citirano: 20.04.2024.]

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Podaci o radu
Naslov (engleski)SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia
AutorTatjana Vilibić-Čavlek
AutorVladimir Stevanovic
AutorMaja Ilić
AutorLjubo Barbić
AutorKrunoslav Capak
AutorIrena Tabain
AutorJasna Lenicek Krleza
AutorThomas Ferenc
AutorZeljka Hruskar
AutorRenata Zrinski Topić
AutorVanja Kaliterna
AutorArlen Antolović-Požgain
AutorJasmina Kučinar
AutorIva Koščak
AutorDijana Mayer
AutorMario Sviben
AutorLjiljana Antolasic
AutorLjiljana Milasincic
AutorLovro Bucić
AutorIvana Ferenčak
AutorBernard Kaić
MBZ: 235003
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus with a pandemic spread. So far, a total of 349,910 SARS-CoV-2 cases and 7687 deaths were reported in Croatia. We analyzed the seroprevalence and neutralizing (NT) antibody response in the Croatian general population after the first (May–July 2020) and second (December 2020–February 2021) pandemic wave. Initial serological testing was performed using a commercial ELISA, with confirmation of reactive samples by a virus neutralization test (VNT). A significant difference in the overall seroprevalence rate was found after the first (ELISA 2.2%, VNT 0.2%) and second waves (ELISA 25.1%, VNT 18.7%). Seropositive individuals were detected in all age groups, with significant differences according to age. The lowest prevalence of NT antibodies was documented in the youngest (<10 years; 16.1%) and the oldest (60–69/70+ years; 16.0% and 12.8%, respectively) age groups. However, these age groups showed the highest median NT titers (32–64). In other groups, seropositivity varied from 19.3% to 21.5%. A significant weak positive correlation between binding antibody level as detected by ELISA and VNT titer (rho = 0.439, p < 0.001) was observed. SARS-CoV-2 NT antibody titers seem to be age-related, with the highest NT activity in children under 10 years and individuals above 50 years.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPathogens
Brojčani podacivol. 10, br. 6, 774
e-ISSN2076-0817
DOIhttps://doi.org/10.3390/pathogens10060774
URN:NBNurn:nbn:hr:105:022605
Datum objave publikacije2021-06-20
URL dokumentahttps://www.mdpi.com/2076-0817/10/6/774
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-06-13 11:27:03