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Treatment of diabetic retinopathy
Treatment of diabetic retinopathy
Pierre Paul Francis Marie Haccart
Diabetic Retinopathy (DR) is the most common complication of diabetes and is the leading cause of vision-loss in working-age adults in industrialized countries. As the prevalence of diabetes in population worldwide is increasing, the prevalence of DR is also increasing. Reasons leading to the increase prevalence of DR also include the aging of the population and the increase in life expectancy in diabetic patient, duration of disease being one of the main risk factors for the development of...
Treatment of gestational diabetes
Treatment of gestational diabetes
Noga Ben Haim
Pregnant women with GDM have a higher risk of both short- and long-term consequences and complications, including complications during labor, macrosomia, and T2DM in both the mother and her fetus. Modifiable changes such as physical activity and diet, as well as blood glucose monitoring is essential in dealing with GDM. The diet suggested for women with GDM should be targeted specifically to each patient and provide enough energy while keeping the normoglycemic range. The aim is to...
Treatment of idiopathic infertility
Treatment of idiopathic infertility
Priyanka Rani Oseatunro Ugbade
Idiopathic infertility is defined as the failure to achieve pregnancy after 12 months of unprotected sexual intercourse, without a known cause. Idiopathic infertility affects 15-30% of couples trying to conceive. Various aetiologies have been suggested as the cause of idiopathic infertility. In men and women, the immune system plays a role in conception, hence defects in this pathway could be a possible cause. Lifestyle and habits, such as having a high BMI or poor sleep quality, have also...
Treatment of ovarian hyperstimulation syndrome
Treatment of ovarian hyperstimulation syndrome
Silvija Metelko
Ovarian hyperstimulation syndrome (OHSS) is a rare complication of controlled ovarian hyperstimulation and ovulation induction that despite better preventative methods, continues to develop in some patients undergoing assisted reproduction. Patients with mild to moderate OHSS can be managed conservatively by reducing ascites and restoring intravascular volume. Patients with severe OHSS are always treated as inpatients and may require admission to the intensive care unit where they can also...
Treatment of patients with post-traumatic stress disorder
Treatment of patients with post-traumatic stress disorder
Mayan Menashes
Post-traumatic stress disorder is a chronic and disabling disorder, which poses a significant public health issue for which existing therapies are only somewhat effective, and ongoing investigation and research are still being conducted to find the most appropriate treatment. The disorder affects 15- 24% of the population who were exposed to a traumatic event in their lifetime. Although 60 percent to 50 percent of men and women, respectively, experienced traumatic or life-threatening...
Treatment of pregnant women with preterm premature rupture of membranes in prevention of adverse neurological consequences of a child
Treatment of pregnant women with preterm premature rupture of membranes in prevention of adverse neurological consequences of a child
Lirose Bracha
Preterm premature rupture of membranes (PPROM) occurs in 3% of all pregnancies and is responsible for around one-third of all preterm births, resulting in more frequent perinatal morbidity and fetal death. Generally, complications of PPROM increase in frequency and severity as gestational age decreases. PPROM has been linked to several risk factors, including PPROM in a previous pregnancy, maternal cigarette smoking, and importantly urogenital tract infections, leading to chorioamnionitis....
Treatment of severe acne
Treatment of severe acne
Marko Koželj
Acne vulgaris is a chronic inflammatory condition of the pilosebaceous unit, typically starting at puberty. The prevalence rate of 85% has been estimated among persons aged 12-24 years. Acne formation is influenced by four major factors: androgen-induced increased sebum production, altered keratinization within the follicle, increased colonization of the pilosebaceous duct Cutibacterium acnes, and release of inflammatory mediators. Clinical features include non-inflammatory lesions...
Treatment of the late complications of hip and femur fractures
Treatment of the late complications of hip and femur fractures
Thomas De Sousa
Orthopedic surgeons deal with deformities, diseases of bones and joints, and injuries to the musculoskeletal system. Orthopedic injuries are injuries to the skeletal system which consists of bones, joints and supporting structures like muscles, cartilage, ligaments and tendons. The term "orthopedic injury" includes fractures (broken bones), dislocated joints (dislocation) and torn or ruptured tendons, muscles or ligaments. The term "fracture" is defined as the disruption in the integrity...
Treatment options for infections caused by carbapenem-resistant Klebsiella pneumoniae isolates
Treatment options for infections caused by carbapenem-resistant Klebsiella pneumoniae isolates
Luka Joakim Csenar
Carbapenem-resistant Klebsiella pneumoniae poses a global public health threat. Newly emerging resistances deplete the antibiotic armamentarium and represent a therapeutic challenge even for the most experienced physician. Epidemiological data on carbapenemresistant K. pneumoniae show high mortality rates and growing resistance rates. Carbapenems are broad-spectrum β-lactam antibiotics being used in complicated and hard to treat infections including those caused by K. pneumoniae. The...
Treatment options for moderate to severe psoriasis
Treatment options for moderate to severe psoriasis
Chen Siboni
Psoriasis is a T-cell-mediated illness that affects a large percentage of the population. Psoriasis is increasingly recognized as a multi-system inflammatory condition, rather than only a skin disease. In addition, the disease's chronicity has a major psychological impact on the patient's and cares quality of life. To arrest the so-called psoriatic march, proper illness management is crucial. Because there is no one-size-fits-all treatment for psoriasis, lifestyle changes, comorbidities,...
Trendovi incidencije i mortaliteta od mezotelioma u Hrvatskoj od 2001. do 2021. godine
Trendovi incidencije i mortaliteta od mezotelioma u Hrvatskoj od 2001. do 2021. godine
Drago Baković
Cilj: Cilj ovog rada je istražiti trendove incidencije i mortaliteta za mezoteliom u Republici Hrvatskoj u razdoblju od 2001. do 2021. godine i usporediti ih s drugim populacijama. Metode: Podaci o incidenciji i mortalitetu mezotelioma za period od 2001. do 2021. godine preuzeti su iz baza Hrvatskog zavoda za javno zdravstvo. Dobno-standardizirane stope incidencije i mortaliteta izračunate su metodom direktne standardizacije koristeći Standardno europsko stanovništvo. Trendove...
Trendovi u propisivanju benzodiazepina u Republici Hrvatskoj
Trendovi u propisivanju benzodiazepina u Republici Hrvatskoj
Luka Šižgorić
Benzodiazepini su lijekovi koji se često propisuju, osobito među starijom populacijom, bez obzira na činjenicu kako su poznati rizici koji su povezani s njihovom upotrebom te unatoč smjernicama koje preporučuju njihovu kratkotrajnu primjenu. Uočava se rastući trend potrošnje benzodiazepina u Hrvatskoj. Benzodiazepini spadaju u terapijsku skupinu N05-Psiholeptici prema ATK klasifikaciji, koja se u posljednjih 15 godina nalazi uvijek unutar prve tri skupine prema ukupnoj godišnjoj...

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