Koronarografija kompjutoriziranom tomografijom u obradi bolesnika s koronarnim stentovima i premosnicama

master's thesis

• Title (english): Coronary computed tomography angiography in assessment of patients with coronary stents and bypass grafts
• Author: Ana Anđelić
• Mentor: Maja Hrabak Paar (mentor)
• Committee member: Maja Prutki (predsjednik povjerenstva)
• Committee member: Gordana Ivanac (član povjerenstva)
• Committee member: Maja Hrabak Paar (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Radiology); Zagreb
• Defense date and country: 2024-09-18, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Radiology

Abstract

Koronarna bolest (CAD, engl. coronary artery disease) je karakterizirana nakupljanjem aterosklerotskih plakova u arterijama koje opskrbljuju srce krvlju. Ova bolest može biti opstruktivna ili neopstruktivna, a liječenje uključuje promjene u životnom stilu, lijekove i invazivne intervencije. CAD je kronična i često progresivna bolest, s potencijalom za naglo pogoršanje zbog rupture ili erozije plaka.
Koronarna kompjutorizirana tomografska angiografija (CCTA) postala je ključna za dijagnosticiranje CAD-a jer pruža detaljan uvid u stanje arterija i razvoj plakova. Napredak u CCTA tehnologiji omogućio je smanjenje izloženosti zračenju i preciznu karakterizaciju arterija, što je značajno za donošenje medicinskih odluka. CCTA se koristi za praćenje promjena u plakovima i za stratifikaciju rizika kod pacijenata.
Revaskularizacija miokarda, bilo putem perkutane koronarne intervencije ili kirurške metode (aortokoronarno premoštenje, CABG), igra važnu ulogu u liječenju opstruktivnog CAD-a. CCTA je također korisna za procjenu prohodnosti stentova i aortokoronarnih premosnica. CCTA ima važnu ulogu u praćenju pacijenata nakon revaskularizacije, pružajući informacije o prohodnosti žila i statusu aterosklerotskih plakova. Korištenje CCTA za praćenje revaskularizacije može značajno doprinijeti poboljšanju ishoda liječenja i smanjenju komplikacija. U ovom preglednom radu prikazana je uloga CCTA u obradi bolesnika nakon revaskularizacije miokarda.

Abstract (english)

Coronary artery disease (CAD) is characterized by the accumulation of atherosclerotic plaques in the arteries that supply the heart with blood. This disease can be obstructive or non-obstructive, and treatment includes lifestyle changes, medications, and invasive interventions. CAD is a chronic and often progressive disease, with the potential for sudden worsening due to plaque rupture or erosion.
Coronary computed tomography angiography (CCTA) has become essential for diagnosing CAD as it provides detailed insights into the condition of the arteries and plaque development. Advances in CCTA technology have enabled reduced radiation exposure and precise characterization of the arteries, which is crucial for medical decision-making. CCTA is used to monitor changes in plaques and to stratify risk in patients.
Myocardial revascularization, either through percutaneous coronary intervention or surgically (coronary artery bypass grafting, CABG), plays an important role in the treatment of obstructive CAD. CCTA is also useful for assessing the patency of stents and coronary bypass grafts. CCTA plays an important role in monitoring patients after revascularization, providing information on vessel patency and the status of atherosclerotic plaques. The use of CCTA for revascularization monitoring can significantly contribute to improving treatment outcomes and reducing complications. In this review paper, we describe the role of CCTA in the evaluation of patients after myocardial revascularization.

• Keywords: koronarna bolest; koronarna kompjutorizirana tomografska angiografija; revaskularizacija miokarda
• Keywords (english): coronary artery disease; coronary computed tomography angiography; myocardial revascularization
• Language: croatian
• URN:NBN: urn:nbn:hr:105:684244
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-09-12 11:15:26