Rekonstrukcije baze lubanje nakon endoskopske endonazalne kirurgije – analiza 164 slučaja

Scientific paper - Review paper

• Author: Marcel Marjanović Kavanagh https://orcid.org/0000-0001-9084-6787
• Author: Katarina Đurić Vuković
• Author: Gorazd Poje
• Author: Vjerislav Peterković
• Author: Dinko Leović
• Author's institution: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract (croatian)

Odrediti naše rezultate rekonstrukcije defekta baze lubanje kod bolesnika operiranih endoskopskim endonazalnim pristupom za patologiju prednje i srednje lubanjske baze.
Retrospektivna analiza 164 bolesnika s patologijom prednje i srednje lubanjske baze, operiranih endoskopskim endonazalnim pristupom u razdoblju od 2018. do 2021. godine i minimalnim trajanjem praćenja od tri mjeseca postoperativno.
U navedenom razdoblju smanjili smo postoperativne stope likvoreje na 2,4% u odnosu na prethodno razdoblje 2014. – 2018. godine, kada je stopa likvoreja iznosila 12,4%. Prema stupnjevima intraoperativnog nalaza defekta dure stope likvoreje iznosile su kako slijedi: za 0. stupanj 0%, 1. stupanj 3,85%, 2. stupanj 8,3%, i 3. stupanj 6,9%.
Pokazali smo da se pažljivim pristupom i planiranjem rekonstrukcija defekata baze lubanje stopa likvoreja smanjuje. Rezultati naše studije na 164 pacijenta sa stupnjem postoperativne likvoreje od 2,4% u komparaciji sa svjetskom literaturom pokazuju da po stopama postoperativnih likvoreja pratimo svjetske standarde.

Abstract (english)

Aim of the study: To show our postoperative cerebrospinal fluid (CSF) leak rate for patients who
underwent endoscopic endonasal approach for anterior and middle fossa pathology. Materials and methods:
Retrospective analysis of 164 patients with anterior and middle fossa pathology, operated via endoscopic endonasal approach between 2018 and 2021, with minimal postoperative follow-up of three months. Results: We
managed to reduce the postoperative CSF leak rate from 12.4% (2014–2018) to 2.4%. The CSF leaks were as
following: grade 0, 0%, grade 1, 3.85%, grade 2, 8.3%, grade 3 6.9%. Conclusion: A planned graded approach in
managing skull base defects reduces the postoperative CSF leak rate. Our CSF leak rate of 2.4% is comparable with
international standards for endoscopic endonasal approach.

• Keywords (croatian): Deskriptori BAZA LUBANJE – kirurgija; PREDNJA LUBANJSKA JAMA – kirurgija, patologija; SREDNJA LUBANJSKA JAMA – kirurgija, patologija; LIKVOREJA – epidemiologija; TRANSFERIN – analiza; POSLIJEOPERACIJSKE KOMPLIKACIJE – epidemiologija; REKONSTRUKCIJSKI KIRURŠKI ZAHVATI – metode; ENDOSKOPIJA – metode; KIRURŠKI REŽNJEVI; RETROSPEKTIVNA ISTRAŽIVANJA
• Keywords (english): SKULL BASE – surgery; CRANIAL FOSSA, ANTERIOR – pathology, surgery; CRANIAL FOSSA, MIDDLE – pathology, surgery; CEREBROSPINAL FLUID LEAK – epidemiology; TRANSFERRIN – analysis; POSTOPERATIVE COMPLICATIONS – epidemiology; RECONSTRUCTIVE SURGICAL PROCEDURES – methods; ENDOSCOPY – methods; SURGICAL FLAPS; RETROSPECTIVE STUDIES
• Language: croatian
• Publication type: Scientific paper - Review paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Liječnički vjesnik
• Numbering: vol. 143, no. 7-8, pp. 277-283
• p-ISSN: 0024-3477
• e-ISSN: 1849-2177
• DOI: https://doi.org/10.26800/LV-143-7-8-8
• URN:NBN: urn:nbn:hr:105:039388
• Publication: 2021
• Document URL: https://hrcak.srce.hr/261915
• Type of resource: Text
• Access conditions: Open access
• Created on: 2022-01-14 09:34:13