prikaz prve stranice dokumenta Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
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Scientific paper - Original scientific paper
Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
Diagnostics, 14 (2024), 7; 779. https://doi.org/10.3390/diagnostics14070779
Duvančić, Tea; Vukasović Barišić, Andreja; Čizmić, Ana; Plečko, Mihovil; Bohaček, Ivan; Delimar, Domagoj

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Duvančić, T., Vukasović Barišić, A., Čizmić, A., Plečko, M., Bohaček, I. & Delimar, D. (2024). Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip. Diagnostics, 14. (7). doi: 10.3390/diagnostics14070779

Duvančić, Tea, et al. "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip." Diagnostics, vol. 14, no. 7, 2024. https://doi.org/10.3390/diagnostics14070779

Duvančić, Tea, Andreja Vukasović Barišić, Ana Čizmić, Mihovil Plečko, Ivan Bohaček and Domagoj Delimar. "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip." Diagnostics 14, no. 7 (2024). https://doi.org/10.3390/diagnostics14070779

Duvančić, T., et al. (2024) 'Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip', Diagnostics, 14(7). doi: 10.3390/diagnostics14070779

Duvančić T, Vukasović Barišić A, Čizmić A, Plečko M, Bohaček I, Delimar D. Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip. Diagnostics [Internet]. 2024 April 08 [cited 2025 March 14];14(7). doi: 10.3390/diagnostics14070779

T. Duvančić, A. Vukasović Barišić, A. Čizmić, M. Plečko, I. Bohaček and D. Delimar, "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip", Diagnostics, vol. 14, no. 7, April 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:348952. [Accessed: 14 March 2025]

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Metadata
Title (english)Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
AuthorTea Duvančić
AuthorAndreja Vukasović Barišić
AuthorAna Čizmić
AuthorMihovil Plečko
AuthorIvan Bohaček
AuthorDomagoj Delimar
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Orthopedics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Orthopedics
Abstract (english)
Developmental dysplasia of the hip (DDH) presents varying degrees of femoral head dislocation, with severe cases leading to the formation of a new articular surface on the external side of the iliac bone—the neoacetabulum. Despite conventional understanding suggesting otherwise, a tissue resembling hyaline cartilage is found in the neoacetabulum and acetabulum of Crowe III and IV patients, indicating a potential for hyaline cartilage development without mechanical pressure. To test this theory, acetabular and femoral head cartilage obtained from patients with DDH was stained with hematoxylin–eosin and toluidine blue. The immunohistochemical analysis for collagen types II and VI and aggrecan was performed, as well as delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) analysis on a 7.0 T micro-MRI machine. The results obtained from DDH patients were compared to those of the control groups. Hyaline cartilage was found in the neoacetabulum and the acetabulum of patients with DDH. The nature of the tissue was confirmed with both the histological and the MRI analyses. The results of this study proved the presence of hyaline cartilage in patients with DDH at anatomical regions genetically predisposed to be bone tissue and at regions that are not subjected to mechanical stress. This is the first time that the neoacetabular cartilage of patients with advanced stages of DDH has been characterized in detail.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleDiagnostics
Numberingvol. 14, no. 7, 779
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics14070779
URN:NBNurn:nbn:hr:105:348952
Publication2024-04-08
ProjectNumber: IP-2018-01-3688
Title (croatian): Karakterizacija hrskavice acetabuluma i femura u odraslih bolesnika s razvojnim poremećajem kuka
Title (english): Acetabular and femoral cartilage characterization in adult patients with developmental dysplasia of the hip
Acronym: HIPoCART
Leader: Domagoj Delimar
Jurisdiction: Croatia
Funding stream: Research Projects
Document URLhttps://www.mdpi.com/2075-4418/14/7/779
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2025-03-12 13:41:52