prikaz prve stranice dokumenta Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
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Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
Diagnostics, 14 (2024), 7; 779. https://doi.org/10.3390/diagnostics14070779
Duvančić, Tea; Vukasović Barišić, Andreja; Čizmić, Ana; Plečko, Mihovil; Bohaček, Ivan; Delimar, Domagoj

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Duvančić, T., Vukasović Barišić, A., Čizmić, A., Plečko, M., Bohaček, I. i Delimar, D. (2024). Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip. Diagnostics, 14. (7). doi: 10.3390/diagnostics14070779

Duvančić, Tea, et al. "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip." Diagnostics, vol. 14, br. 7, 2024. https://doi.org/10.3390/diagnostics14070779

Duvančić, Tea, Andreja Vukasović Barišić, Ana Čizmić, Mihovil Plečko, Ivan Bohaček i Domagoj Delimar. "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip." Diagnostics 14, br. 7 (2024). https://doi.org/10.3390/diagnostics14070779

Duvančić, T., et al. (2024) 'Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip', Diagnostics, 14(7). doi: 10.3390/diagnostics14070779

Duvančić T, Vukasović Barišić A, Čizmić A, Plečko M, Bohaček I, Delimar D. Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip. Diagnostics [Internet]. 08.04.2024. [pristupljeno 14.03.2025.];14(7). doi: 10.3390/diagnostics14070779

T. Duvančić, A. Vukasović Barišić, A. Čizmić, M. Plečko, I. Bohaček i D. Delimar, "Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip", Diagnostics, vol. 14, br. 7, Travanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:348952. [Citirano: 14.03.2025.]

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Podaci o radu
Naslov (engleski)Specificities in the Structure of the Cartilage of Patients with Advanced Stages of Developmental Dysplasia of the Hip
AutorTea Duvančić
AutorAndreja Vukasović Barišić
AutorAna Čizmić
AutorMihovil Plečko
AutorIvan Bohaček
AutorDomagoj Delimar
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA ORTOPEDIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ortopedija
Sažetak (engleski)
Developmental dysplasia of the hip (DDH) presents varying degrees of femoral head dislocation, with severe cases leading to the formation of a new articular surface on the external side of the iliac bone—the neoacetabulum. Despite conventional understanding suggesting otherwise, a tissue resembling hyaline cartilage is found in the neoacetabulum and acetabulum of Crowe III and IV patients, indicating a potential for hyaline cartilage development without mechanical pressure. To test this theory, acetabular and femoral head cartilage obtained from patients with DDH was stained with hematoxylin–eosin and toluidine blue. The immunohistochemical analysis for collagen types II and VI and aggrecan was performed, as well as delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) analysis on a 7.0 T micro-MRI machine. The results obtained from DDH patients were compared to those of the control groups. Hyaline cartilage was found in the neoacetabulum and the acetabulum of patients with DDH. The nature of the tissue was confirmed with both the histological and the MRI analyses. The results of this study proved the presence of hyaline cartilage in patients with DDH at anatomical regions genetically predisposed to be bone tissue and at regions that are not subjected to mechanical stress. This is the first time that the neoacetabular cartilage of patients with advanced stages of DDH has been characterized in detail.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 14, br. 7, 779
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics14070779
URN:NBNurn:nbn:hr:105:348952
Datum objave publikacije2024-04-08
ProjektŠifra: IP-2018-01-3688
Naziv (hrvatski): Karakterizacija hrskavice acetabuluma i femura u odraslih bolesnika s razvojnim poremećajem kuka
Naziv (engleski): Acetabular and femoral cartilage characterization in adult patients with developmental dysplasia of the hip
Kratica: HIPoCART
Voditelj: Domagoj Delimar
Pravna nadležnost: Hrvatska
Financijer: Hrvatska zaklada za znanost
Linija financiranja: Research Projects
URL dokumentahttps://www.mdpi.com/2075-4418/14/7/779
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-03-12 13:41:52