Tomosinteza dojke

master's thesis

• Title (english): Breast tomosynthesis
• Author: Ana Abičić
• Mentor: Gordana Ivanac (mentor)
• Committee member: Boris Brkljačić (predsjednik povjerenstva)
• Committee member: Milan Radoš (član povjerenstva)
• Committee member: Gordana Ivanac (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Radiology); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Radiology

Abstract

Mamografija je jedna od najčešće korištenih metoda slikovnog prikaza dojki i jedina dokazano učinkovita metoda probira populacije za karcinom dojke. Digitalna tomosinteza novija je metoda oslikavanja dojki koja predstavlja napredak u odnosu na konvencionalnu digitalnu mamografiju. Koristi pokretnu rendgensku cijev koja se kreće po luku iznad dojke, omogućujući tako dobivanje više snimki po jednoj projekciji, od kojih svaka prikazuje jedan sloj dojke. Sintetska mamografija je cjeloviti dvodimenzionalni prikaz podataka dobivenih tomosintezom. Uvođenjem pregleda tomosintezom uz dodatak sintetske mamografije možemo povećati stopu detekcije karcinoma dojke u odnosu na dvodimenzionalnu digitalnu mamografiju, uz otprilike jednaku dozu zračenja kao i kod digitalne mamografije. Cilj ovog rada je prikazati mogućnosti tomosinteze u odnosu na dvodimenzionalnu digitalnu mamografiju te opisati njenu ulogu u probiru za karcinom dojke. Posebno ćemo se osvrnuti na njenu ulogu u oslikavanju gustih dojki čiji mamografski nalazi imaju posebno nisku specifičnost i osjetljivost. Također je cilj prikazati najnovije spoznaje vezane uz napredak tomosinteze, posebno mogućnost biopsije pod nadzorom tomosinteze te moguću primjenu umjetne inteligencije u očitavanju nalaza tomosinteze.

Abstract (english)

Mammography is one of the most commonly used breast imaging methods and the only screening method for breast cancer scientifically proven to be effective. Digital tomosynthesis is a newer method of breast imaging that represents advance over conventional digital mammography. It uses a movable X-ray tube that moves in an arc above the breast, thus allowing multiple images to be obtained per projection, each showing a single layer of breast. Synthetic mammography is a complete two-dimensional display of data obtained by tomosynthesis. By introducing tomosynthesis screening with the addition of synthetic mammography, the detection rate of breast cancer can be increased compared to two-dimensional digital mammography, with approximately the same radiation dose as with digital mammography. The aim of this paper is to present the possibilities of tomosynthesis in relation to two-dimensional digital mammography and to describe its role in screening for breast cancer. Special attention will be paid to its role in imaging of dense breasts, whose mammographic findings have a particularly low specificity and sensitivity. The aim is also to present the latest knowledge related to the progress of tomosynthesis, especially the possibility of biopsy under the supervision of tomosynthesis and the possible application of artificial intelligence in reading the findings of tomosynthesis.

• Keywords: radiografija; dojka; probir populacije; mamografija
• Keywords (english): radiography; breast; mass screening; mammography
• Language: croatian
• URN:NBN: urn:nbn:hr:105:330319
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-04-19 07:52:21