Prediktori kliničkog ishoda nakon potrebe izvantjelesnom membranskom oksigenacijom

master's thesis

• Title (english): Predictors of clinical outcome among patients supported with extracorporeal membrane oxygenation
• Author: Mihaela Stanec
• Mentor: Hrvoje Gašparović (mentor)
• Committee member: Mladen Perić (predsjednik povjerenstva)
• Committee member: Tomislav Meštrović (član povjerenstva)
• Committee member: Hrvoje Gašparović (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities); Zagreb
• Defense date and country: 2014-09-24, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Nursing

Abstract

Pojam izvantjelesne potpore (ECMO) podrazumijeva primjenu produljena izvantjelesnoga krvotoka uglavnom putem izvanprsne kanilacije u bolesnika sa akutnim, reverzibilnim urušajem srčane ili respiracijske funkcije koja ne odgovara na konzervativno liječenje. Sa druge strane, produljeno izvantjelesno liječenje se također provodi kao opcija za oporavak srčanog mišića i slabosti desnog srca nakon kardiokirurškog zahvata na otvorenom srcu. Tada je kanilacija najčešće centralnog tipa. U proceduri ekstrakorporalnog održavanja života koriste se uređaji zvani oksigenatori.Cilj: utvrditi funkcionalnost oksigenatora.Hipoteza: Stupanj antikoagulacije korelira sa efikasnošću transfera plinova.Materijali i metode: Retrospektivnom studijom obuhvaćeno je 30 bolesnika koji su nakon operacije na otvorenom srcu imali indikaciju za ECMO potporom. Dokazano je da su praćeni laboratorijski parametri ključni za učinkovitost transfera O2 i CO2.

Abstract (english)

The term extracorporeal membrane oxygeneation (ECMO) implies appliance of long-term extracorporeal support usually via extrathoracic cannulation, in patients with acute, reversible cardiac or respiratory failure who are unresponsive to conservative treatment. On the other hand, prolonged extracorporeal treatment is also performed as an option for myocardial recovery and weakness of the right side of the heart after open heart surgery. In that case type of cannulation is usually central. In extracorporeal life support procedure there is a use of appliances called oxygenators.Goal: determine oxygenator functionality.Hypothesis: degree of anticoagulation correlates with gass transfer efficiency.Materials and methods: 30 patients that had an indication for ECMO support after open heart surgery were included in retrospective study. It is shown that the monitored laboratory parameters are crucial for O2 and CO2 transfer.

• Keywords: delta O2; delta CO2; oksigenator; koagulacijski parametri
• Keywords (english): delta O2; delta CO2; oxygenator; koagulation parameters
• Language: croatian
• URN:NBN: urn:nbn:hr:105:740479
• Study programme: Title: Studies in Nursing; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-11-06 14:01:35