prikaz prve stranice dokumenta Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement
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Scientific paper - Original scientific paper
Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement
Radiology: Cardiothoracic Imaging, 2 (2020), 2; e190090. https://doi.org/10.1148/ryct.2020190090
Hrabak-Paar, Maja; Kircher, Achim; Al Sayari, Saeed; Kopp, Sebastien; Santini, Francesco; Schmieder, Roland E.; Kachenoura, Nadjia; Yates, Denise; Langenickel, Thomas; Bremerich, Jens; Heye, Tobias

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Hrabak Paar, M., Kircher, A., Al Sayari, S., Kopp, S., Santini, F., Schmieder, R. E. ... Heye, T. (2020). Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement. Radiology: Cardiothoracic Imaging, 2. (2). doi: 10.1148/ryct.2020190090

Hrabak Paar, Maja, et al. "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement." Radiology: Cardiothoracic Imaging, vol. 2, no. 2, 2020. https://doi.org/10.1148/ryct.2020190090

Hrabak Paar, Maja, Achim Kircher, Saeed Al Sayari, Sebastien Kopp, Francesco Santini, Roland E. Schmieder, Nadjia Kachenoura, et al. "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement." Radiology: Cardiothoracic Imaging 2, no. 2 (2020). https://doi.org/10.1148/ryct.2020190090

Hrabak Paar, M., et al. (2020) 'Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement', Radiology: Cardiothoracic Imaging, 2(2). doi: 10.1148/ryct.2020190090

Hrabak Paar M, Kircher A, Al Sayari S, Kopp S, Santini F, Schmieder RE, and sur.. Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement. Radiology: Cardiothoracic Imaging [Internet]. 2020 April 30 [cited 2024 October 20];2(2). doi: 10.1148/ryct.2020190090

M. Hrabak Paar, et al., "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement", Radiology: Cardiothoracic Imaging, vol. 2, no. 2, April 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:228448. [Accessed: 20 October 2024]

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Metadata
Title (english)Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement
AuthorMaja Hrabak-Paar
AuthorAchim Kircher
AuthorSaeed Al Sayari
AuthorSebastien Kopp
AuthorFrancesco Santini
AuthorRoland E. Schmieder
AuthorNadjia Kachenoura
AuthorDenise Yates
AuthorThomas Langenickel
AuthorJens Bremerich
AuthorTobias Heye
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Radiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Abstract (english)
Purpose: To assess intraobserver, interobserver, and scan-rescan variability of MRI aortic stiffness measurements in a multicenter trial setting. ----- Materials and methods: This study was a retrospective analysis of prospectively collected data in a multicenter prospective clinical trial (clinicaltrials.gov ID NCT01870739). Forty-five adult patients (31 men; mean age, 58 years ± 12 [standard deviation]; 15 patients per center; three centers) with arterial hypertension underwent standardized 3-T baseline MRI assessments between June and September 2014. Aortic strain was calculated from maximum and minimum aortic area measurements repeated three times by three readers at three aortic levels on three retrospectively gated axial gradient-echo (GRE) data sets. Pulse wave velocity (PWV) was assessed three times by five readers as Δx/Δt: Δx was measured on a parasagittal GRE image of the aortic arch, and Δt was extracted from ascending and descending aortic velocity curves created on three axial phase-contrast acquisitions. Intraobserver, interobserver, and scan-rescan variability was calculated using percentage coefficient of variation (COV). ----- Results: Aortic strain variability was lowest at the level of the distal descending aorta (DDA) with median COVs of 1.6% for intraobserver variability, 4.0% for interobserver variability, and 10.3% for scan-rescan variability. It was highest at the ascending aorta (AA) with COVs of 3.6% for intraobserver variability, 10.7% for interobserver variability, and 19.8% for scan-rescan variability. Variability of PWV was low: 0.7% for intraobserver variability, 1.5% for interobserver variability, and 8.1% for scan-rescan variability. ----- Conclusion: Low variability can be achieved for aortic strain and PWV measurements in a multicenter trial setting using standardized MRI protocols. Although COV was lower when measuring aortic strain at DDA compared with AA, variability was acceptable at both anatomic locations.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleRadiology: Cardiothoracic Imaging
Numberingvol. 2, no. 2, e190090
e-ISSN2638-6135
DOIhttps://doi.org/10.1148/ryct.2020190090
URN:NBNurn:nbn:hr:105:228448
Publication2020-04-30
Document URLhttp://pubs.rsna.org/doi/10.1148/ryct.2020190090
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-05-19 10:39:49