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Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement
Radiology: Cardiothoracic Imaging, 2 (2020), 2; e190090. https://doi.org/10.1148/ryct.2020190090
Hrabak-Paar, Maja; Kircher, Achim; Al Sayari, Saeed; Kopp, Sebastien; Santini, Francesco; Schmieder, Roland E.; Kachenoura, Nadjia; Yates, Denise; Langenickel, Thomas; Bremerich, Jens; Heye, Tobias

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Hrabak Paar, M., Kircher, A., Al Sayari, S., Kopp, S., Santini, F., Schmieder, R. E. ... Heye, T. (2020). Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement. Radiology: Cardiothoracic Imaging, 2. (2). doi: 10.1148/ryct.2020190090

Hrabak Paar, Maja, et al. "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement." Radiology: Cardiothoracic Imaging, vol. 2, br. 2, 2020. https://doi.org/10.1148/ryct.2020190090

Hrabak Paar, Maja, Achim Kircher, Saeed Al Sayari, Sebastien Kopp, Francesco Santini, Roland E. Schmieder, Nadjia Kachenoura, et al. "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement." Radiology: Cardiothoracic Imaging 2, br. 2 (2020). https://doi.org/10.1148/ryct.2020190090

Hrabak Paar, M., et al. (2020) 'Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement', Radiology: Cardiothoracic Imaging, 2(2). doi: 10.1148/ryct.2020190090

Hrabak Paar M, Kircher A, Al Sayari S, Kopp S, Santini F, Schmieder RE, i sur.. Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement. Radiology: Cardiothoracic Imaging [Internet]. 30.04.2020. [pristupljeno 05.10.2024.];2(2). doi: 10.1148/ryct.2020190090

M. Hrabak Paar, et al., "Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement", Radiology: Cardiothoracic Imaging, vol. 2, br. 2, Travanj 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:228448. [Citirano: 05.10.2024.]

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Naslov (engleski)Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement
AutorMaja Hrabak-Paar
AutorAchim Kircher
AutorSaeed Al Sayari
AutorSebastien Kopp
AutorFrancesco Santini
AutorRoland E. Schmieder
AutorNadjia Kachenoura
AutorDenise Yates
AutorThomas Langenickel
AutorJens Bremerich
AutorTobias Heye
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA RADIOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Radiologija
Sažetak (engleski)
Purpose: To assess intraobserver, interobserver, and scan-rescan variability of MRI aortic stiffness measurements in a multicenter trial setting. ----- Materials and methods: This study was a retrospective analysis of prospectively collected data in a multicenter prospective clinical trial (clinicaltrials.gov ID NCT01870739). Forty-five adult patients (31 men; mean age, 58 years ± 12 [standard deviation]; 15 patients per center; three centers) with arterial hypertension underwent standardized 3-T baseline MRI assessments between June and September 2014. Aortic strain was calculated from maximum and minimum aortic area measurements repeated three times by three readers at three aortic levels on three retrospectively gated axial gradient-echo (GRE) data sets. Pulse wave velocity (PWV) was assessed three times by five readers as Δx/Δt: Δx was measured on a parasagittal GRE image of the aortic arch, and Δt was extracted from ascending and descending aortic velocity curves created on three axial phase-contrast acquisitions. Intraobserver, interobserver, and scan-rescan variability was calculated using percentage coefficient of variation (COV). ----- Results: Aortic strain variability was lowest at the level of the distal descending aorta (DDA) with median COVs of 1.6% for intraobserver variability, 4.0% for interobserver variability, and 10.3% for scan-rescan variability. It was highest at the ascending aorta (AA) with COVs of 3.6% for intraobserver variability, 10.7% for interobserver variability, and 19.8% for scan-rescan variability. Variability of PWV was low: 0.7% for intraobserver variability, 1.5% for interobserver variability, and 8.1% for scan-rescan variability. ----- Conclusion: Low variability can be achieved for aortic strain and PWV measurements in a multicenter trial setting using standardized MRI protocols. Although COV was lower when measuring aortic strain at DDA compared with AA, variability was acceptable at both anatomic locations.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaRadiology: Cardiothoracic Imaging
Brojčani podacivol. 2, br. 2, e190090
e-ISSN2638-6135
DOIhttps://doi.org/10.1148/ryct.2020190090
URN:NBNurn:nbn:hr:105:228448
Datum objave publikacije2020-04-30
URL dokumentahttp://pubs.rsna.org/doi/10.1148/ryct.2020190090
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2021-05-19 10:39:49