Primjena blockchain tehnologije u kliničkoj farmakologiji

master's thesis

• Title (english): Application of blockchain technology in clinical pharmacology
• Author: Tin Šklebar
• Mentor: Robert Likić (mentor)
• Committee member: Milan Milošević (predsjednik povjerenstva)
• Committee member: Jasenka Markeljević (član povjerenstva)
• Committee member: Robert Likić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2021-07-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Clinical Pharmacology and Toxicology
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Blockchain je tehnologija raspodijeljene glavne knjige (engl. Distributed Ledger Technology, DLT) bazirana na mrežnoj arhitekturi ravnopravnih računara (eng. peer-to-peer, P2P), koja je osigurana naprednom kriptografijom i koristi konsenzusni mehanizam za dogovaranje transakcija, dok je pritom kontrola nad mrežom decentralizirana. Glavne prednosti blockchain tehnologije mogu se sažeti u tri glavne karakteristike: decentralizacija, transparentnost i nepromjenjivost. Primjena ove tehnologije u kliničkoj farmakologiji može imati mnogo potencijalnih koristi. Najveće prednosti koje bi primjena ove tehnologije mogla donijeti su sprječavanje ulaska krivotvorenih lijekova u opskrbni lanac, jeftinije i vremenski učinkovitije provođenje kliničkih ispitivanja, kao i mogućnost pružanja pristupa podacima o pacijentima istraživačima u stvarnom vremenu. Ova tehnologija se također može koristiti za nadzor i praćenje slučajeva pacijenata sa COVID-19 tijekom pandemije. Iako blockchain tehnologija postaje sve istaknutija, ova tehnologija je još uvijek poprilično nova i mnogima nepoznata, a jedan od glavnih problema su potencijalno visoki troškovi uvođenja i održavanja zdravstvenih blockchain protokola. Očekuje se da će u idućih 5 godina blockchain pronaći svoj put u više aspekata zdravstvene zaštite, a među prvim područjima usvajanja su financijske transakcije u zdravstvenim sustavima.

Abstract (english)

Blockchain is defined as distributed ledger technology (DLT) built around a peer-to-peer computer network, which is secured using advanced cryptography and uses a consensus mechanism to agree upon transactions, whereby control remains decentralized. The main appeal of the blockchain technology is based on its three major characteristics: decentralization, transparency and immutability. As such, implementing blockchain in clinical pharmacology could have several benefits. The greatest advantages that the implementation of this technology could bring include: preventing counterfeited drugs from entering the supply chain, cheaper and more time efficient conduct of clinical trials as well as providing researchers with access to real time patient data. Moreover, blockchain can be used for surveillance and case tracking of Covid-19 patients during the pandemic. Still, this technology is fairly new with very few professional developers and currently it is hard to predict the overall costs of blockchain implementation and maintenance in healthcare. However, it is expected that in the next 5 years, blockchain will find its way into multiple aspects of healthcare, with first areas of adoption involving financial transactions and medication tracking in healthcare.

• Keywords: blockchain tehnologija; klinička ispitivanja; klinička farmakologija
• Keywords (english): blockchain technology; clinical trials; clinical pharmacology
• Language: croatian
• URN:NBN: urn:nbn:hr:105:807027
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-05-12 09:14:40