Primjena metode bioimpedance u procjeni volumnog statusa bolesnika sa završnim stadijem kronične bubrežne bolesti

master's thesis

• Title (english): Use of bioimpedance in the assessment of volume status of patiens with end-stage chronic kidney disease
• Author: Marjelka Trkulja
• Mentor: Nikolina Bašić Jukić (mentor)
• Committee member: Petar Kes
• Committee member: Jasenka Markeljević
• Committee member: Nikolina Bašić Jukić
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2015-09-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Kronična bubrežna bolest je bolest u kojoj dolazi do smanjenja funkcije bubrega. Bolesnici sa završnim stadijem kronične bubrežne bolesti moraju krenuti s nadomjesnom bubrežnom terapijom. Nadomještanje bubrežne funkcije može biti peritonejskom dijalizom, hemodijalizom ili transplantacijom bubrega. Peritonejska dijaliza se odvija preko potrbušnice bolesnika, hemodijaliza preko sintetske membrane – dijalizatora, a transplantacija bubrega može biti od živog ili umrlog darovatelja organa.
Broj bolesnika s kroničnom bubrežnom bolesti je u laganom porastu, medijan godina bolesnika koji započinju s liječenjem se stalno kreće prema starijoj dobi (67. godina), a najčešće osnovno oboljenje koje dovodi do kronične bubrežne bolesti je šećerna bolest.
Na prvim tretmanima, bolesnicima se određuje „suha težina“ čije postizanje je cilj svakog tretmana. Hiperhidracija je višak tekućine kod bolesnika na dijalizi. Zadržavanje tekućine kod bubrežnih bolesnika je normalno i posljedica same bolesti.
Osim nalaza hiperhidracije, aparat sa bioimpedancijskom spektroskopijom omogućava i uvid u nutricijski status bolesnika. Dokazivanje viška tekućine je bio kompleksan problem koji je olakšan mjerenjem hiperhidracije aparatom s bioimpedancijskom spektroskopijom.
Analizom bolesnika aparatom s bioimpedancijskom spektroskopijom olakšava se rad zdravstvenom osoblju na odjelima za dijalizu jer im pomaže u planiranju liječenja i edukacije bolesnika.
U bilježenju i tumačenju podataka dobivenih mjerenjem bioimpedancijskom spektroskopijom od velike pomoći je i povezani kompjutorski program.

Abstract (english)

Chronic renal disease is a disease with loss of kidney function. Patients with end-stage renal disease must start with renal replacement therapy. Renal Replacement Therapy can be a peritoneal dialysis, haemodialysis or kidney transplantation. Peritoneal dialysis is carried out over peritoneum of the patient; haemodialysis uses a synthetic membrane – dialyzer;
a kidney transplant can be from living or deceased organ donors.
The number of patients with chronic kidney disease is slowly increasing, with median age of patients starting treatment constantly moving towards an older age (67 years), while the most common underlying disease that leads to chronic kidney disease is diabetes mellitus.
During initial treatments, "dry weight" is determined for patients. Hyperhydration is excess fluid in patients on dialysis. Fluid retention in kidney patients is normal and a result of the disease. Achievement of dry weight is the goal of every treatment.
Proving excess fluid is a complex problem, which can be overcome more easily by measuring hyperhydration with device with Bioimpedance spectroscopy.
In addition to the determination of the hyperhydration, bioimpedance spectroscopy gives an insight into the nutritional status of the patients as well.
Device with Bioimpedance spectroscopy simplifies the work of medical staff in the dialysis wards as it helps in planning patient treatment and their education.
Appropriate software can help can recording and interpretation of data gathered with bioimpedance spectroscopy device.

• Keywords: kronična bubrežna bolest; hemodijaliza; peritonejska dijaliza; hiperhidracija; bioimpedancijska spektroskopija
• Keywords (english): chronic kidney disease; haemodialysis; peritoneal dialysis; overhydration; bioimpedance spectroscopy
• Language: croatian
• URN:NBN: urn:nbn:hr:105:901198
• Study programme: Title: Studies in Nursing; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-04-20 12:26:01