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The complexity of malnutrition in cystic fibrosis
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Romana Prskalo Cystic Fibrosis (CF) is the most common life-limiting genetic disease of Caucasian populations. It is a disease inherited in an autosomal recessive fashion and the defect lies in the gene encoding the cystic fibrosis transmembrane regulator (CFTR) - a chloride channel regulating ion transport across the apical surface of secretory epithelial cells. The main clinical manifestations are pancreatic insufficiency and progressive obstructive pulmonary and gastrointestinal disease. Malnutrition in...
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The effect of endocrine disruptors on reproductive health
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Dor Yanai Synthetic chemicals are causing significant environmental contamination in several industrial and agricultural applications. Pesticides, plasticizers, antimicrobials, and flame retardants have positive purposes, but their consequences on human health are a global issue. Endocrine-disrupting chemicals (EDCs) can alter hormonal homeostasis, leading to developmental and reproductive problems. Human EDC exposure is linked to obesity, metabolic syndrome, and type 2 diabetes in new in vitro, in...
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The effect of general anesthesia on the quality of sleep
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Matea Mataković Trivunčević General anesthesia is a procedure performed every day worldwide due to numerous surgical and nonsurgical indications. It produces pronounced changes in the patient’s body homeostasis, primarily due to the drugs used to achieve the state of general anesthesia. The most frequent components of general anesthesia are various sedative, analgesic and hypnotic drugs, all of which exert their effects through acting on receptors in the central nervous system. The effects produced by these drugs are...
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The ever growing complexity of trophoblast epigenetics
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Katharina Alexandra Schmidt Mammalian placentation is closely regulated by the actions of trophoblast cells at the time of implantation. Invasion of trophoblast into uterine tissue is an essential process in placentation and appropriate fetal development. Since human trophoblast is responsible for appropriate fetal growth, it is of major interest in the field of medicine, particularly in understanding how it is
influenced by different processes and environmental conditions. This review is sought to give an insight into...
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The impact of Covid-19 Epidemic on general population mental health
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Ivana Katarina Grašić Introduction The Covid-19 epidemic represents general psychosocial stressor, which affected all individuals in given society. The aim of the thesis is to analyze the impact the corona virus disease 2019 (Covid-19) had on mental health, depression, anxiety, suicide, and stress in the general population. Methods The methods used to obtain the articles were through PubMed, with keywords of General population and Covid-19. This review article will analyze and summarize the findings of a few...
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The impact of changes in neonatal intensive care practices on short-term outcomes of premature infants
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Anna Mara Hrgetić Vitols OBJECTIVE: To assess the changes in neonatal care practices at the NICU-UHC Zagreb and their impact on short-term morbidity of a cohort of premature infants. A comparison between two epochs was performed, the periods before and after changes in respiratory support, healthcare professionals' attitudes and practices in supporting and promoting the breastfeeding, and laboratory phlebotomy reduction was introduced. ----- METHODS: We performed a retrospective study to investigate short-term...
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The importance of external version in breech presentation on frequency of caesarean section
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Eva Drevenšek External cephalic version is a procedure in which fetus is manually turned into a cephalic presentation. Its importance lies in the fact that there is a high rate of caesareans section in breech presentation and this technique is used to achieve a cephalic position in which chances for a vaginal birth increase and the risk of caesarean section can be reduced. It is useful in breech and other non-cephalic presentations. It can be done at term or before term. Although recommended, its use it...
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The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds
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Viviana Wahl Vacuum assisted closure therapy was developed for the needs of plastic surgery in the 90s. Primarily used for the treatment of patients with large chronic wounds, the usage nowadays extends to area of medicine and veterinary, for all types of large, chronic and infected wounds, where increased drainage of the exudate and help with wound closure is needed. Vacuum assisted closure therapy uses sub-atmospheric pressure between 50 and 200 mmHg which facilitates drainage of fluids, reduces...
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The outcome of assisted reproductive techniques in women with autoimmune disorders
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Lital Sarit Abadi Infertility is estimated to affect about 8-12% of reproductive-aged couples across the globe. It is a clinical manifestation of different etiological factors, which may affect males, females, or both. The distribution of the most common causes affecting female fertility varies among different countries; and in developed countries it usually involves disorders of ovulation, endometriosis, pelvic adhesions, fallopian tube blockage, as well as hyperprolactinemia. Autoimmune diseases may also...
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The prevalence of cardiovascular risks in HIV-infected persons in care in Croatia in 2015
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Ivan Raymond Marius Desbordes Aim:This review will aim at considering the prevalence of cardiovascular risks among the HIV-infected population undergoing ART therapy in Croatia: Cardiovascular diseases are now among the most common causes of mortality in people living with HIV. We will see for which reasons people living with HIV appear to have an elevated risk for cardiovascular diseases. ----- Method: A cross-sectional analysis of 310 consecutive HIV infected patients seen during a routine clinical visit aged 40 to 79...
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The relationship between doctor's health and safe patient care
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Amanda Josephine Lam Safe patient care is an aspect of healthcare that is becoming increasingly recognized by the world’s healthcare professionals as a crucial component of optimal patient outcome. Patient safety places emphasis on a physician’s duty to report, analyze and prevent medical errors. Safe patient care is highly dependent upon a competent and functioning physician. The psychological
and physical health of a doctor is vital in ensuring safe patient outcome. Today’s medical professionals have...
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The role of 3D computing planning in maxillofacial surgery
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Alban Gecaj The role of 3D computing in reconstructive surgery is still not clearly established, yet the advancements of virtual surgical planning (VSP) and its implementation for various indications is slowly elucidating its purpose.
VSP consist of multiple techniques which are being used to complement surgery in its planning stage as well as during it. Such techniques can be divided into computer assisted surgery (CAS), computer assisted design (CAD) and computer assisted manufacturing (CAM)....
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