prikaz prve stranice dokumenta Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome
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Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome
Antioxidants, 13 (2024), 3; 339. https://doi.org/10.3390/antiox13030339
Klobučar, Iva; Hofmann, Lidija; Habisch, Hansjörg; Lechleitner, Margarete; Klobučar, Lucija; Trbušić, Matias; Pregartner, Gudrun; Berghold, Andrea; Madl, Tobias; Frank, Saša; Degoricija, Vesna

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Klobučar, I., Hofmann, L., Habisch, H., Lechleitner, M., Klobučar, L., Trbušić, M. ... Degoricija, V. (2024). Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome. Antioxidants, 13. (3). doi: 10.3390/antiox13030339

Klobučar, Iva, et al. "Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome." Antioxidants, vol. 13, br. 3, 2024. https://doi.org/10.3390/antiox13030339

Klobučar, Iva, Lidija Hofmann, Hansjörg Habisch, Margarete Lechleitner, Lucija Klobučar, Matias Trbušić, Gudrun Pregartner, et al. "Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome." Antioxidants 13, br. 3 (2024). https://doi.org/10.3390/antiox13030339

Klobučar, I., et al. (2024) 'Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome', Antioxidants, 13(3). doi: 10.3390/antiox13030339

Klobučar I, Hofmann L, Habisch H, Lechleitner M, Klobučar L, Trbušić M, i sur.. Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome. Antioxidants [Internet]. 11.03.2024. [pristupljeno 19.12.2024.];13(3). doi: 10.3390/antiox13030339

I. Klobučar, et al., "Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome", Antioxidants, vol. 13, br. 3, Ožujak 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:003833. [Citirano: 19.12.2024.]

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Naslov (engleski)Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome
AutorIva Klobučar
AutorLidija Hofmann
AutorHansjörg Habisch
AutorMargarete Lechleitner
AutorLucija Klobučar
AutorMatias Trbušić
AutorGudrun Pregartner
AutorAndrea Berghold
AutorTobias Madl
AutorSaša Frank
AutorVesna Degoricija
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The association between advanced oxidation protein products (AOPPs) and lipoprotein subclasses remains unexplored. Therefore, we performed comprehensive lipoprotein profiling of serum using NMR spectroscopy and examined the associations of lipoprotein subclasses with the serum levels of AOPPs in healthy volunteers (HVs) and patients with metabolic syndrome (MS). The serum levels of AOPPs were significantly positively correlated with the serum levels of very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and low-density lipoprotein (LDL); however, they were significantly negatively correlated with high-density lipoprotein (HDL). These lipoproteins (and their subclasses) differed markedly regarding the direction of correlations between their lipid contents and AOPPs. The strength of the correlations and the relative contributions of the subclasses to the correlations were different in the HVs and patients with MS. As revealed by orthogonal partial least squares discriminant analyses, the serum levels of IDL were strong determinants of AOPPs in the HVs, whereas the serum levels of VLDL and the lipid content of LDL were strong determinants in both groups. We conclude that IDL, VLDL, and LDL facilitate, whereas HDL diminishes the bioavailability of serum AOPPs. The presence of MS and the lipid contents of the subclasses affect the relationship between lipoproteins and AOPPs.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAntioxidants
Brojčani podacivol. 13, br. 3, 339
e-ISSN2076-3921
DOIhttps://doi.org/10.3390/antiox13030339
URN:NBNurn:nbn:hr:105:003833
Datum objave publikacije2024-03-11
URL dokumentahttps://www.mdpi.com/2076-3921/13/3/339
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-10-22 08:31:25