Vladimir Sertić: forgotten pioneer of virology and bacteriophage therapy

Znanstveni rad - Izvorni znanstveni rad

• Autor: Zdravko Lacković
• Autor: Karlo Toljan
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet; (KATEDRA ZA TEMELJNU I KLINIČKU FARMAKOLOGIJU)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Temeljne medicinske znanosti; Farmakologija

Sažetak (engleski)

Vladimir Sertić was a pioneer of bacteriophage research in the period between the two world wars. He was born and educated in Croatia, where he made his initial discoveries, and joined Félix d'Herelle's Laboratoire du Bactériophage in Paris in 1928. Original documents and a box with hundreds of sealed bacteriophages samples were kept in Sertić's Zagreb home for decades. Following Vladimir's death, his sister passed this archival material to Professor Zdravko Lacković in 1989. Some years later, these artefacts were opened and studied. Additionally, we conducted a literature search using the term ‘Vladimir Sertić’ in the databases PubMed and Google Scholar. After a detailed examination of these data, we established a chronology of his work and compiled a list of his scientific publications. A complete bibliography, with the exception of those publications already cited here, is provided as an appendix. Sertić's key contributions included the exploration of the properties of phage lysins, the devising of a uniform bacteriophage classification system and, in collaboration with his protégé, Nikolai Boulgakov, the isolation of numerous bacteriophage strains, including the famous φX174. Finally it was Sertić's pioneering work in Zagreb that offered confirmation that phages are live agents.

• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Notes and Records: the Royal Society Journal of the History of Science
• Brojčani podaci: vol. 74, br. 4, str. 567-578
• p-ISSN: 0035-9149
• e-ISSN: 1743-0178
• DOI: https://doi.org/10.1098/rsnr.2019.0010
• URN:NBN: urn:nbn:hr:105:975519
• Datum objave publikacije: 2020-01-08
• URL dokumenta: https://royalsocietypublishing.org/doi/10.1098/rsnr.2019.0010
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2020-12-03 09:55:24