Emerging and neglected zoonoses in transplant population

Znanstveni rad - Pregledni rad

• Autor: Anna Mrzljak
• Autor: Rafaela Novak
• Autor: Nenad Pandak
• Autor: Irena Tabain
• Autor: Lucija Franušić
• Autor: Ljubo Barbić
• Autor: Maja Bogdanić
• Autor: Vladimir Savić
• Autor: Danko Mikulić
• Autor: Jadranka Pavičić-Šarić
• Autor: Vladimir Stevanović
• Autor: Tatjana Vilibić-Čavlek
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet; (KATEDRA ZA INTERNU MEDICINU)
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet; (KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti; Interna medicina
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti; Medicinska mikrobiologija

Sažetak (engleski)

Zoonoses represent a problem of rising importance in the transplant population. A close relationship and changes between human, animal and environmental health ("One Health" concept) significantly influence the transmission and distribution of zoonotic diseases. The aim of this manuscript is to perform a narrative review of the published literature on emerging and neglected zoonoses in the transplant population. Many reports on donor-derived or naturally acquired (re-)emerging arboviral infections such as dengue, chikungunya, West Nile, tick-borne encephalitis and Zika virus infection have demonstrated atypical or more complicated clinical course in immunocompromised hosts. Hepatitis E virus has emerged as a serious problem after solid organ transplantation (SOT), leading to diverse extrahepatic manifestations and chronic hepatitis with unfavorable outcomes. Some neglected pathogens such as lymphocytic choriomeningitis virus can cause severe infection with multi-organ failure and high mortality. In addition, ehrlichiosis may be more severe with higher case-fatality rates in SOT recipients. Some unusual or severe presentations of borreliosis, anaplasmosis and rickettsioses were also reported among transplant patients. Moreover, toxoplasmosis as infectious complication is a well-recognized zoonosis in this population. Although rabies transmission through SOT transplantation has rarely been reported, it has become a notable problem in some countries. Since the spreading trends of zoonoses are likely to continue, the awareness, recognition and treatment of zoonotic infections among transplant professionals should be imperative.

• Ključne riječi (engleski): Bacteria; Non-vector borne diseases; Parasites; Solid-organ transplant; Vector-borne diseases; Viruses; Zoonoses
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Pregledni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: World Journal of Transplantation
• Brojčani podaci: vol. 10, br. 3, str. 47-63
• p-ISSN: 2220-3230
• DOI: https://doi.org/10.5500/wjt.v10.i3.47
• URN:NBN: urn:nbn:hr:105:047362
• Datum objave publikacije: 2020-03-31
• URL dokumenta: https://www.wjgnet.com/2220-3230/full/v10/i3/47.htm
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2021-04-16 09:28:45