prikaz prve stranice dokumenta New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis
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New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis
Journal of Clinical and Translational Hepatology, 9 (2021), 1; 51-59. https://doi.org/10.14218/JCTH.2020.00057
Stojsavljević-Shapeski, Sanja; Duvnjak, Marko; Virović-Jukić, Lucija; Hrabar, Davor; Smirčić Duvnjak, Lea

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Stojsavljević Shapeski, S., Duvnjak, M., Virović Jukić, L., Hrabar, D. i Smirčić Duvnjak, L. (2021). New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis. Journal of Clinical and Translational Hepatology, 9. (1), 51-59. doi: 10.14218/JCTH.2020.00057

Stojsavljević Shapeski, Sanja, et al. "New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis." Journal of Clinical and Translational Hepatology, vol. 9, br. 1, 2021, str. 51-59. https://doi.org/10.14218/JCTH.2020.00057

Stojsavljević Shapeski, Sanja, Marko Duvnjak, Lucija Virović Jukić, Davor Hrabar i Lea Smirčić Duvnjak. "New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis." Journal of Clinical and Translational Hepatology 9, br. 1 (2021): 51-59. https://doi.org/10.14218/JCTH.2020.00057

Stojsavljević Shapeski, S., et al. (2021) 'New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis', Journal of Clinical and Translational Hepatology, 9(1), str. 51-59. doi: 10.14218/JCTH.2020.00057

Stojsavljević Shapeski S, Duvnjak M, Virović Jukić L, Hrabar D, Smirčić Duvnjak L. New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis. Journal of Clinical and Translational Hepatology [Internet]. 28.02.2021. [pristupljeno 02.12.2024.];9(1):51-59. doi: 10.14218/JCTH.2020.00057

S. Stojsavljević Shapeski, M. Duvnjak, L. Virović Jukić, D. Hrabar i L. Smirčić Duvnjak, "New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis", Journal of Clinical and Translational Hepatology, vol. 9, br. 1, str. 51-59, Veljača 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:453259. [Citirano: 02.12.2024.]

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Naslov (engleski)New Drugs on the Block—Emerging Treatments for Nonalcoholic Steatohepatitis
AutorSanja Stojsavljević-Shapeski
AutorMarko Duvnjak
AutorLucija Virović-Jukić
AutorDavor Hrabar
AutorLea Smirčić Duvnjak
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Patients with nonalcoholic steatohepatitis (NASH) are at higher risk of progression to advanced stages of fibrosis, cirrhosis, hepatocellular carcinoma and other end-stage liver disease complications. When addressing treatment of NASH, we have limited approved options, and the mainstay of therapy is lifestyle intervention. Extensive research and revelation in the field of pathogenesis of NASH has offered new possibilities of treatment and emerging new drugs that are being tested currently in numerous preclinical and clinical trials. These drugs target almost all steps in the pathogenesis of NASH to improve insulin sensitivity, glucose and lipid metabolism, to inhibit de novo lipogenesis and delivery of lipids to the liver, and to influence apoptosis, inflammation and fibrogenesis. Although NASH is a multifactorial disease, in the future we could identify the predominating pathological mechanism and, by choosing the most appropriate specific medication, tailor the treatment for every patient individually.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical and Translational Hepatology
Brojčani podacivol. 9, br. 1, str. 51-59
p-ISSN2225-0719
e-ISSN2310-8819
DOIhttps://doi.org/10.14218/JCTH.2020.00057
URN:NBNurn:nbn:hr:105:453259
Datum objave publikacije2021-02-28
URL dokumentahttps://www.xiahepublishing.com/2310-8819/JCTH-2020-00057
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2021-06-28 07:53:32