prikaz prve stranice dokumenta Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results
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Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results
PLOS ONE, 16 (2021), 6; e0253468. https://doi.org/10.1371/journal.pone.0253468
Popović Grle, Sanja; Lampalo, Marina; Škrinjarić Cincar, Sanda; Bulat Kardum, Ljiljana; Gudelj, Ivan; Basioli Kasap, Eugenija; Vergles, Mirna; Tudorić, Neven

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Popović Grle, S., Lampalo, M., Škrinjarić Cincar, S., Bulat Kardum, Lj., Gudelj, I., Basioli Kasap, E. ... Tudorić, N. (2021). Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results. PLOS ONE, 16. (6). doi: 10.1371/journal.pone.0253468

Popović Grle, Sanja, et al. "Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results." PLOS ONE, vol. 16, br. 6, 2021. https://doi.org/10.1371/journal.pone.0253468

Popović Grle, Sanja, Marina Lampalo, Sanda Škrinjarić Cincar, Ljiljana Bulat Kardum, Ivan Gudelj, Eugenija Basioli Kasap, Mirna Vergles i Neven Tudorić. "Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results." PLOS ONE 16, br. 6 (2021). https://doi.org/10.1371/journal.pone.0253468

Popović Grle, S., et al. (2021) 'Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results', PLOS ONE, 16(6). doi: 10.1371/journal.pone.0253468

Popović Grle S, Lampalo M, Škrinjarić Cincar S, Bulat Kardum Lj, Gudelj I, Basioli Kasap E, i sur.. Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results. PLOS ONE [Internet]. 29.06.2021. [pristupljeno 05.10.2024.];16(6). doi: 10.1371/journal.pone.0253468

S. Popović Grle, et al., "Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results", PLOS ONE, vol. 16, br. 6, Lipanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:181041. [Citirano: 05.10.2024.]

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Naslov (engleski)Attitudes of Croatian pulmonologists concerning obstacles to earlier, more appropriate use of biologics in severe asthma: Survey results
AutorSanja Popović Grle
AutorMarina Lampalo
AutorSanda Škrinjarić Cincar
AutorLjiljana Bulat Kardum
AutorIvan Gudelj
AutorEugenija Basioli Kasap
AutorMirna Vergles
AutorNeven Tudorić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Aims: Biologics have been proven efficacious for patients with severe asthma (SA). It is essential to diagnose such individuals correctly. This study was designed to survey pulmonologists to identify barriers to early diagnosis and subsequent appropriate use of biologics for SA in Croatia. ----- Methods: A pulmonologist group with expertise in SA developed the initial list of questions, with the final questionnaire created according to a 2-round Delphi method. The resulting survey consisted of 23 items consequently divided into 4 domains: 1) Pulmonologists' demographics and professional experiences; 2) Concerns about asthma management; 3) Attitudes toward SA diagnosis; and 4) Beliefs and attitudes regarding the use of biologics in managing SA. The given answers represented the respondents' estimates. ----- Results: Eighty-four surveys were analyzed, with pulmonologists observing that general practitioners often inaccurately diagnose asthma and treat acute exacerbations. Although specialist centers are capably and correctly equipped, the time to diagnose patients with SA is approximately 3.5 months, with initial use of biologics delayed an additional 2 months. The primary indications for prescribing biologics are conventional therapy with oral glucocorticoids (91.7%) and frequent acute exacerbations (82.1%). In addition to improper diagnosis (64.3%), many patients with SA do not receive the indicated biologics owing to strict administrative directives for reimbursement (70.2%) or limited hospital resources (57.1%). ----- Limitations: The limitations of this survey include the subjective nature of the collected data, the relatively small sample size, and the lack of the biologic efficacy evaluation. ----- Conclusions: Croatian pulmonologists observed that a significant number of patients with SA who are eligible for biologics are not prescribed them, largely because of an inaccurate and/or delayed diagnosis, a delayed referral to a specialist center, highly restrictive criteria for reimbursement, and/or institutional budgetary limitations.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPLOS ONE
Brojčani podacivol. 16, br. 6, e0253468
e-ISSN1932-6203
DOIhttps://doi.org/10.1371/journal.pone.0253468
URN:NBNurn:nbn:hr:105:181041
Datum objave publikacije2021-06-29
URL dokumentahttps://dx.plos.org/10.1371/journal.pone.0253468
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-11-26 09:56:44