prikaz prve stranice dokumenta N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus
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N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus
Pharmaceutics, 13 (2021), 12; 2082. https://doi.org/10.3390/pharmaceutics13122082
Đelmiš, Josip; Ivanišević, Marina; Horvatiček, Marina

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Đelmiš, J., Ivanišević, M. i Horvatiček, M. (2021). N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus. Pharmaceutics, 13. (12). doi: 10.3390/pharmaceutics13122082

Đelmiš, Josip, et al. "N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus." Pharmaceutics, vol. 13, br. 12, 2021. https://doi.org/10.3390/pharmaceutics13122082

Đelmiš, Josip, Marina Ivanišević i Marina Horvatiček. "N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus." Pharmaceutics 13, br. 12 (2021). https://doi.org/10.3390/pharmaceutics13122082

Đelmiš, J., Ivanišević, M. i Horvatiček, M. (2021) 'N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus', Pharmaceutics, 13(12). doi: 10.3390/pharmaceutics13122082

Đelmiš J, Ivanišević M, Horvatiček M. N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus. Pharmaceutics [Internet]. 04.12.2021. [pristupljeno 01.12.2024.];13(12). doi: 10.3390/pharmaceutics13122082

J. Đelmiš, M. Ivanišević i M. Horvatiček, "N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus", Pharmaceutics, vol. 13, br. 12, Prosinac 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:385939. [Citirano: 01.12.2024.]

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Naslov (engleski)N-3 PUFA and Pregnancy Preserve C-Peptide in Women with Type 1 Diabetes Mellitus
AutorJosip Đelmiš
AutorMarina Ivanišević
AutorMarina Horvatiček
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA GINEKOLOGIJU I OPSTETRICIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Type 1 diabetes (T1DM) is an autoimmune disease characterized by the gradual loss of β-cell function and insulin secretion. In pregnant women with T1DM, endogenous insulin production is absent or minimal, and exogenous insulin is required to control glycemia and prevent ketoacidosis. During pregnancy, there is a partial decrease in the activity of the immune system, and there is a suppression of autoimmune diseases. These changes in pregnant women with T1DM are reflected by Langerhans islet enlargement and improved function compared to pre-pregnancy conditions. N-3 polyunsaturated fatty acids (n-3 PUFA) have a protective effect, affect β-cell preservation, and increase endogenous insulin production. Increased endogenous insulin production results in reduced daily insulin doses, better metabolic control, and adverse effects of insulin therapy, primarily hypoglycemia. Hypoglycemia affects most pregnant women with T1DM and is several times more common than that outside of pregnancy. Strict glycemic control improves the outcome of pregnancy but increases the risk of hypoglycemia and causes maternal complications, including coma and convulsions. The suppression of the immune system during pregnancy increases the concentration of C-peptide in women with T1DM, and n-3 PUFA supplements serve as the additional support for a rise in C-peptide levels through its anti-inflammatory action.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPharmaceutics
Brojčani podacivol. 13, br. 12, 2082
e-ISSN1999-4923
DOIhttps://doi.org/10.3390/pharmaceutics13122082
URN:NBNurn:nbn:hr:105:385939
Datum objave publikacije2021-12-04
ProjektŠifra: IP-2018-01-1284
Naziv (hrvatski): Prevencija hipoglikemije u trudnica s dijabetesom tipa 1
Kratica: PRE-HYPO
Voditelj: Marina Ivanišević
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP
URL dokumentahttps://www.mdpi.com/1999-4923/13/12/2082
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-01-28 10:08:29