prikaz prve stranice dokumenta Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study
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Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study
Journal of Clinical Medicine, 10 (2021), 13; 2914. https://doi.org/10.3390/jcm10132914
Albshesh, Ahmad; Taylor, Joshua; Savarino, Edoardo V.; Truyens, Marie; Armuzzi, Alessandro; Ribaldone, Davide G.; Shitrit, Ariella Bar-Gil; Fibelman, Morine; Molander, Pauliina; Liefferinckx, Claire; Nancey, Stephane; Korani, Mohamed; Rutka, Mariann; Barreiro-de Acosta, Manuel; Domislovic, Viktor; Suris, Gerard; Eriksson, Carl; Alves, Catarina; Mpitouli, Afroditi; di Jiang, Caroline; Tepeš, Katja; Coletta, Marina; Foteinogiannopoulou, Kalliopi; Gisbert, Javier P.; Amir-Barak, Hadar; Attauabi, Mohamed; Seidelin, Jakob; Afif, Waqqas; Marinelli, Carla; Lobaton, Triana; Pugliese, Daniela; Maharshak, Nitsan; Cremer, Anneline; Limdi, Jimmy K.; Molnár, Tamás; Otero-Alvarin, Borja; Krznarić, Željko; Magro, Fernando; Karmiris, Konstantinos; Raine, Tim; Drobne, David; Koutroubakis, Ioannis; Chaparro, Maria; Yanai, Henit; Burisch, Johan; Kopylov, Uri Više autora...

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Albshesh, A., Taylor, J., Savarino, E. V., Truyens, M., Armuzzi, A., Ribaldone, D. G. ... Kopylov, U. (2021). Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study. Journal of Clinical Medicine, 10. (13). doi: 10.3390/jcm10132914

Albshesh, Ahmad, et al. "Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study." Journal of Clinical Medicine, vol. 10, br. 13, 2021. https://doi.org/10.3390/jcm10132914

Albshesh, Ahmad, Joshua Taylor, Edoardo V. Savarino, Marie Truyens, Alessandro Armuzzi, Davide G. Ribaldone, Ariella Bar Gil Shitrit, et al. "Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study." Journal of Clinical Medicine 10, br. 13 (2021). https://doi.org/10.3390/jcm10132914

Albshesh, A., et al. (2021) 'Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study', Journal of Clinical Medicine, 10(13). doi: 10.3390/jcm10132914

Albshesh A, Taylor J, Savarino EV, Truyens M, Armuzzi A, Ribaldone DG, i sur.. Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study. Journal of Clinical Medicine [Internet]. 29.06.2021. [pristupljeno 04.10.2024.];10(13). doi: 10.3390/jcm10132914

A. Albshesh, et al., "Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study", Journal of Clinical Medicine, vol. 10, br. 13, Lipanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:153868. [Citirano: 04.10.2024.]

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Naslov (engleski)Effectiveness of Third-Class Biologic Treatment in Crohn’s Disease: A Multi-Center Retrospective Cohort Study
AutorAhmad Albshesh
AutorJoshua Taylor
AutorEdoardo V. Savarino
AutorMarie Truyens
AutorAlessandro Armuzzi
AutorDavide G. Ribaldone
AutorAriella Bar-Gil Shitrit
AutorMorine Fibelman
AutorPauliina Molander
AutorClaire Liefferinckx
AutorStephane Nancey
AutorMohamed Korani
AutorMariann Rutka
AutorManuel Barreiro-de Acosta
AutorViktor Domislovic
AutorGerard Suris
AutorCarl Eriksson
AutorCatarina Alves
AutorAfroditi Mpitouli
AutorCaroline di Jiang
AutorKatja Tepeš
AutorMarina Coletta
AutorKalliopi Foteinogiannopoulou
AutorJavier P. Gisbert
AutorHadar Amir-Barak
AutorMohamed Attauabi
AutorJakob Seidelin
AutorWaqqas Afif
AutorCarla Marinelli
AutorTriana Lobaton
AutorDaniela Pugliese
AutorNitsan Maharshak
AutorAnneline Cremer
AutorJimmy K. Limdi
AutorTamás Molnár
AutorBorja Otero-Alvarin
AutorŽeljko Krznarić
MBZ: 75865
AutorFernando Magro
AutorKonstantinos Karmiris
AutorTim Raine
AutorDavid Drobne
AutorIoannis Koutroubakis
AutorMaria Chaparro
AutorHenit Yanai
AutorJohan Burisch
AutorUri Kopylov
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Multiple studies have described the effectiveness of ustekinumab (UST) and vedolizumab (VDZ) in patients with Crohn's disease (CD) failing anti- Tumor necrosis factors (TNFs); however, the effectiveness of VDZ or UST as a third-class biologic has not yet been described. ----- Aims and methods: In this retrospective multicenter cohort study, we aimed to investigate the effectiveness of VDZ and UST as a third-class biologic in patients with CD. ----- Results: Two-hundred and four patients were included; 156/204 (76%) patients received VDZ as a second- and UST as a third-class therapy (group A); the remaining 48/204 (24%) patients received UST as a second- and VDZ as a third-class therapy (group B). At week 16-22, 87/156 (55.5%) patients and 27/48 (56.2%) in groups A and B, respectively, responded to treatment (p = 0.9); 41/156 (26.2%) and 15/48 (31.2%) were in clinical remission (p = 0.5). At week 52; 89/103 (86%) patients and 25/29 (86.2%) of the patients with available data had responded to third-class treatment in groups A and B, respectively (p = 0.9); 31/103 (30%) and 47/29 (24.1%) were in clinical remission (p = 0.5). ----- Conclusion: Third-class biological therapy was effective in more than half of the patients with CD. No differences in effectiveness were detected between the use of VDZ and UST as a third-class agent.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 10, br. 13, 2914
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm10132914
URN:NBNurn:nbn:hr:105:153868
Datum objave publikacije2021-06-29
URL dokumentahttps://www.mdpi.com/2077-0383/10/13/2914
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-06-10 09:42:00