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Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods
International Journal of Molecular Sciences, 23 (2022), 5; 2547. https://doi.org/10.3390/ijms23052547
Himelreich-Perić, Marta; Katušić-Bojanac, Ana; Hohšteter, Marko; Sinčić, Nino; Mužić-Radović, Vedrana; Ježek, Davor

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Himelreich Perić, M., Katušić Bojanac, A., Hohšteter, M., Sinčić, N., Mužić Radović, V. i Ježek, D. (2022). Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods. International Journal of Molecular Sciences, 23. (5). doi: 10.3390/ijms23052547

Himelreich Perić, Marta, et al. "Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods." International Journal of Molecular Sciences, vol. 23, br. 5, 2022. https://doi.org/10.3390/ijms23052547

Himelreich Perić, Marta, Ana Katušić Bojanac, Marko Hohšteter, Nino Sinčić, Vedrana Mužić Radović i Davor Ježek. "Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods." International Journal of Molecular Sciences 23, br. 5 (2022). https://doi.org/10.3390/ijms23052547

Himelreich Perić, M., et al. (2022) 'Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods', International Journal of Molecular Sciences, 23(5). doi: 10.3390/ijms23052547

Himelreich Perić M, Katušić Bojanac A, Hohšteter M, Sinčić N, Mužić Radović V, Ježek D. Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods. International Journal of Molecular Sciences [Internet]. 25.02.2022. [pristupljeno 05.10.2024.];23(5). doi: 10.3390/ijms23052547

M. Himelreich Perić, A. Katušić Bojanac, M. Hohšteter, N. Sinčić, V. Mužić Radović i D. Ježek, "Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods", International Journal of Molecular Sciences, vol. 23, br. 5, Veljača 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:732111. [Citirano: 05.10.2024.]

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Podaci o radu
Naslov (engleski)Mast Cells in the Mammalian Testis and Epididymis—Animal Models and Detection Methods
AutorMarta Himelreich-Perić
AutorAna Katušić-Bojanac
AutorMarko Hohšteter
AutorNino Sinčić
AutorVedrana Mužić-Radović
AutorDavor Ježek
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA HISTOLOGIJU I EMBRIOLOGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU BIOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Citologija, histologija i embriologija
Sažetak (engleski)
Mast cells (MCs) are an evolutionary well-conserved type of cells, mediating and modulating allergic responses in innate immunity and tissue remodeling after chronic inflammation. Among other tissues, they inhabit both the testis and epididymis. In the testis, MCs usually appear in the interstitial compartment in humans, but not in other standard experimental models, like rats and mice. MCs seem to be responsible for testicular tissue fibrosis in different causes of infertility. Although experimental animal models follow the effect on MC activation or penetration to the interstitial tissue like in humans to some extent, there is an inconsistency in the available literature regarding experimental design, animal strain, and detection methods used. This comprehensive review offers an insight into the literature on MCs in mammalian testes and epididymides. We aimed to find the most suitable model for research on MC and offer recommendations for future experimental designs. When using in vivo animal models, tunica albuginea incorporation and standard histological assessment need to be included. Domesticated boar strains kept in modified controlled conditions exhibit the highest similarity to the MC distribution in the human testis. 3D testicular models are promising but need further fine-tuning to become a valid model for MC investigation.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Molecular Sciences
Brojčani podacivol. 23, br. 5, 2547
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms23052547
URN:NBNurn:nbn:hr:105:732111
Datum objave publikacije2022-02-25
ProjektŠifra: KK.01.1.1.01.0008
Naziv (hrvatski): Znanstveni centar izvrsnosti za reproduktivnu i regenerativnu medicinu – istraživanja novih platformi i potencijala
Voditelj: Slobodan Vukičević
Pravna nadležnost: eu
Financijer: EK
URL dokumentahttps://www.mdpi.com/1422-0067/23/5/2547
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-10-05 08:36:12