prikaz prve stranice dokumenta The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group
  Preuzmi
PDF 1.24 MB
Znanstveni rad - Izvorni znanstveni rad
The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group
Viruses, 14 (2022), 5; 972. https://doi.org/10.3390/v14050972
Kowalska, Justyna D.; Bieńkowski, Carlo; Fleischhans, Lukáš; Antoniak, Sergii; Skrzat-Klapaczyńska, Agata; Suchacz, Magdalena; Bogdanić, Nikolina; Gokengin, Deniz; Oprea, Cristiana; Karpov, Igor; Kase, Kerstin; Matulionyte, Raimonda; Papadopoulos, Antonios; Rukhadze, Nino; Harxhi, Arjan; Jilich, David; Lakatos, Botond; Sedlacek, Dalibor; Dragovic, Gordana; Vasylyev, Marta; Verhaz, Antonia; Yancheva, Nina; Begovac, Josip; Horban, Andrzej Više autora...

Citirajte ovaj rad

Kowalska, J. D., Bieńkowski, C., Fleischhans, L., Antoniak, S., Skrzat Klapaczyńska, A., Suchacz, M. ... Horban, A. (2022). The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group. Viruses, 14. (5). doi: 10.3390/v14050972

Kowalska, Justyna D., et al. "The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group." Viruses, vol. 14, br. 5, 2022. https://doi.org/10.3390/v14050972

Kowalska, Justyna D., Carlo Bieńkowski, Lukáš Fleischhans, Sergii Antoniak, Agata Skrzat Klapaczyńska, Magdalena Suchacz, Nikolina Bogdanić, et al. "The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group." Viruses 14, br. 5 (2022). https://doi.org/10.3390/v14050972

Kowalska, J. D., et al. (2022) 'The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group', Viruses, 14(5). doi: 10.3390/v14050972

Kowalska JD, Bieńkowski C, Fleischhans L, Antoniak S, Skrzat Klapaczyńska A, Suchacz M, i sur.. The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group. Viruses [Internet]. 05.05.2022. [pristupljeno 17.08.2024.];14(5). doi: 10.3390/v14050972

J. D. Kowalska, et al., "The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group", Viruses, vol. 14, br. 5, Svibanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:692901. [Citirano: 17.08.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:692901
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group
AutorJustyna D. Kowalska
AutorCarlo Bieńkowski
AutorLukáš Fleischhans
AutorSergii Antoniak
AutorAgata Skrzat-Klapaczyńska
AutorMagdalena Suchacz
AutorNikolina Bogdanić
AutorDeniz Gokengin
AutorCristiana Oprea
AutorIgor Karpov
AutorKerstin Kase
AutorRaimonda Matulionyte
AutorAntonios Papadopoulos
AutorNino Rukhadze
AutorArjan Harxhi
AutorDavid Jilich
AutorBotond Lakatos
AutorDalibor Sedlacek
AutorGordana Dragovic
AutorMarta Vasylyev
AutorAntonia Verhaz
AutorNina Yancheva
AutorJosip Begovac
AutorAndrzej Horban
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INFEKTOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
HIV-positive patients may present lungs with multiple infections, which may hinder differential diagnoses and the choice of treatment in the course of COVID-19, especially in countries with limited access to high-standard healthcare. Here, we aim to investigate the association between radiological changes and poor COVID-19 outcomes among HIV-positive patients from Central and Eastern Europe. Between November 2020 and May 2021, the Euroguidelines in Central and Eastern Europe Network Group started collecting observational data on HIV and COVID-19 co-infections. In total, 16 countries from Central and Eastern European submitted data (eCRF) on 557 HIV-positive patients. The current analyses included patients who had a radiological examination performed. Logistic regression models were used to identify the factors associated with death, ICU admission, and partial recovery (poor COVID-19 outcomes). Factors that were significant in the univariate models (p < 0.1) were included in the multivariate model. Radiological data were available for 224 (40.2%) patients, 108 (48.2%) had computed tomography, and 116 (51.8%) had a chest X-ray. Of these, 211 (94.2%) were diagnosed using RT-PCR tests, 212 (94.6%) were symptomatic, 123 (55.6%) were hospitalized, 37 (16.6%) required oxygen therapy, and 28 (13.1%) either died, were admitted to ICU, or only partially recovered. From the radiologist’s description, 138 (61.6%) patients had typical radiological changes, 18 (8.0%) atypical changes, and 68 (30.4%) no changes. In the univariate models, CD4 count (OR = 0.86 [95% CI: 0.76–0.98]), having a comorbidity (2.33 [1.43–3.80]), HCV and/or HBV co-infection (3.17 [1.32–7.60]), being currently employed (0.31 [0.13–0.70]), being on antiretroviral therapy (0.22 [0.08–0.63]), and having typical (3.90 [1.12–13.65]) or atypical (10.8 [2.23–52.5]) radiological changes were all significantly associated with poor COVID-19 outcomes. In the multivariate model, being on antiretroviral therapy (OR = 0.20 [95% CI:0.05–0.80]) decreased the odds of poor COVID-19 outcomes, while having a comorbidity (2.12 [1.20–3.72]) or either typical (4.23 [1.05–17.0]) or atypical (6.39 [1.03–39.7]) radiological changes (vs. no changes) increased the odds of poor COVID-19 outcomes. Among HIV patients diagnosed with symptomatic SARS-CoV-2 infection, the presence of either typical or atypical radiological COVID-19 changes independently predicted poorer outcomes.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaViruses
Brojčani podacivol. 14, br. 5, 972
e-ISSN1999-4915
DOIhttps://doi.org/10.3390/v14050972
URN:NBNurn:nbn:hr:105:692901
Datum objave publikacije2022-05-05
URL dokumentahttps://www.mdpi.com/1999-4915/14/5/972
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-12-15 08:15:18