prikaz prve stranice dokumenta A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database
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A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database
European Journal of Cardio-Thoracic Surgery, 63 (2023), 2; ezac514. https://doi.org/10.1093/ejcts/ezac514
Arabkhani, Bardia; Klautz, Robert J M; de Heer, Frederiek; De Kerchove, Laurent; El Khoury, Gebrine; Lansac, Emmanuel; Schäfers, Hans-Joachim; El-Hamamsy, Ismail; Lenoir, Marien; Aramendi, José I; Meuris, Bart; Verbrugghe, Peter; Kluin, Jolanda; Koolbergen, Dave R; Bouchot, Olivier; Rudež, Igor; Kolesar, Adrian; van Brakel, Thomas J Više autora...

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Arabkhani, B., Klautz, R. J. M., de Heer, F., De Kerchove, L., El Khoury, G., Lansac, E. ... van Brakel, T. J. (2023). A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database. European Journal of Cardio-Thoracic Surgery, 63. (2). doi: 10.1093/ejcts/ezac514

Arabkhani, Bardia, et al. "A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database." European Journal of Cardio-Thoracic Surgery, vol. 63, br. 2, 2023. https://doi.org/10.1093/ejcts/ezac514

Arabkhani, Bardia, Robert J M Klautz, Frederiek de Heer, Laurent De Kerchove, Gebrine El Khoury, Emmanuel Lansac, Hans Joachim Schäfers, et al. "A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database." European Journal of Cardio-Thoracic Surgery 63, br. 2 (2023). https://doi.org/10.1093/ejcts/ezac514

Arabkhani, B., et al. (2023) 'A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database', European Journal of Cardio-Thoracic Surgery, 63(2). doi: 10.1093/ejcts/ezac514

Arabkhani B, Klautz RJM, de Heer F, De Kerchove L, El Khoury G, Lansac E, i sur.. A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database. European Journal of Cardio-Thoracic Surgery [Internet]. 03.02.2023. [pristupljeno 06.10.2024.];63(2). doi: 10.1093/ejcts/ezac514

B. Arabkhani, et al., "A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database", European Journal of Cardio-Thoracic Surgery, vol. 63, br. 2, Veljača 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:621141. [Citirano: 06.10.2024.]

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Naslov (engleski)A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database
AutorBardia Arabkhani
AutorRobert J M Klautz
AutorFrederiek de Heer
AutorLaurent De Kerchove
AutorGebrine El Khoury
AutorEmmanuel Lansac
AutorHans-Joachim Schäfers
AutorIsmail El-Hamamsy
AutorMarien Lenoir
AutorJosé I Aramendi
AutorBart Meuris
AutorPeter Verbrugghe
AutorJolanda Kluin
AutorDave R Koolbergen
AutorOlivier Bouchot
AutorIgor Rudež
AutorAdrian Kolesar
AutorThomas J van Brakel
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA KIRURGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Sažetak (engleski)
Objectives: Our goal was to evaluate the outcome of valve-sparing root replacement (VSRR) and to compare the outcomes to those of patients having composite valve-graft conduit aortic root replacement (CVG-ARR) in a cohort of patients with aortic root aneurysm ± valve insufficiency, without valvular stenosis. Although valve-sparing procedures are preferable in young patients, there is a lack of comparative data in comparable patients. Methods: The VSRR procedures were performed in 2005 patients, and 218 patients underwent a CVG-ARR procedure. Exclusion criteria included aortic dissection, endocarditis and valvular stenosis. Propensity score matching (3:1 ratio) was applied to compare VSRR (reimplantation 33% and remodelling 67%) and CVG-ARR. Results: We matched 218 patients with CVG-ARR to 654 patients with VSRR (median age, 56.0; median follow-up was 4 years in both groups; interquartile range 1-5 years). Early mortality was 1.1% of those who had VSRR versus 2.3% in those who had CVG-ARR. Survival was 95.4% [95% confidence interval (CI) 94-97%] at 5 years in patients who had VSRR versus 85.4% (95% CI 82-92%) in those who had CVG-ARR; P = 0.002. Freedom from reintervention at 5 years was 96.8% (95% CI 95-98%) with VSRR and 95.4% (95% CI 91-99%) with CVG-ARR (P = 0.98). Additionally, there were more thromboembolic, endocarditis and bleeding events in the patients who had CVG-ARR (P = 0.02). Conclusions: This multicentre study shows excellent results after valve-sparing root replacement in patients with an ascending aortic aneurysm with or without valve insufficiency. Compared to composite valve-graft aortic root replacement, survival is better and valve-related events are fewer. Consequently, valve-sparing procedures should be considered whenever a durable repair is feasible. We advocate a valve-sparing strategy even in more complex cases when performed in experienced centres.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaEuropean Journal of Cardio-Thoracic Surgery
Brojčani podacivol. 63, br. 2, ezac514
e-ISSN1873-734X
DOIhttps://doi.org/10.1093/ejcts/ezac514
URN:NBNurn:nbn:hr:105:621141
Datum objave publikacije2023-02-03
URL dokumentahttps://academic.oup.com/ejcts/article/doi/10.1093/ejcts/ezac514/6779980
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2023-08-17 11:54:23