prikaz prve stranice dokumenta The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication
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The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication
PLoS ONE, 9 (2014), 4; e95229. https://doi.org/10.1371/journal.pone.0095229
Klarica, Marijan; Radoš, Milan; Erceg, Gorislav; Petošić, Antonio; Jurjević, Ivana; Orešković, Darko

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Klarica, M., Radoš, M., Erceg, G., Petošić, A., Jurjević, I. i Orešković, D. (2014). The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication. PLoS ONE, 9. (4). doi: 10.1371/journal.pone.0095229

Klarica, Marijan, et al. "The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication." PLoS ONE, vol. 9, br. 4, 2014. https://doi.org/10.1371/journal.pone.0095229

Klarica, Marijan, Milan Radoš, Gorislav Erceg, Antonio Petošić, Ivana Jurjević i Darko Orešković. "The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication." PLoS ONE 9, br. 4 (2014). https://doi.org/10.1371/journal.pone.0095229

Klarica, M., et al. (2014) 'The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication', PLoS ONE, 9(4). doi: 10.1371/journal.pone.0095229

Klarica M, Radoš M, Erceg G, Petošić A, Jurjević I, Orešković D. The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication. PLoS ONE [Internet]. 18.04.2014. [pristupljeno 29.11.2024.];9(4). doi: 10.1371/journal.pone.0095229

M. Klarica, M. Radoš, G. Erceg, A. Petošić, I. Jurjević i D. Orešković, "The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication", PLoS ONE, vol. 9, br. 4, Travanj 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:384911. [Citirano: 29.11.2024.]

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Naslov (engleski)The influence of body position on cerebrospinal fluid pressure gradient and movement in cats with normal and impaired craniospinal communication
AutorMarijan Klarica
AutorMilan Radoš
AutorGorislav Erceg
AutorAntonio Petošić
AutorIvana Jurjević
AutorDarko Orešković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Intracranial hypertension is a severe therapeutic problem, as there is insufficient knowledge about the physiology of cerebrospinal fluid (CSF) pressure. In this paper a new CSF pressure regulation hypothesis is proposed. According to this hypothesis, the CSF pressure depends on the laws of fluid mechanics and on the anatomical characteristics inside the cranial and spinal space, and not, as is today generally believed, on CSF secretion, circulation and absorption. The volume and pressure changes in the newly developed CSF model, which by its anatomical dimensions and basic biophysical features imitates the craniospinal system in cats, are compared to those obtained on cats with and without the blockade of craniospinal communication in different body positions. During verticalization, a long-lasting occurrence of negative CSF pressure inside the cranium in animals with normal cranio-spinal communication was observed. CSF pressure gradients change depending on the body position, but those gradients do not enable unidirectional CSF circulation from the hypothetical site of secretion to the site of absorption in any of them. Thus, our results indicate the existence of new physiological/pathophysiological correlations between intracranial fluids, which opens up the possibility of new therapeutic approaches to intracranial hypertension.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPLoS ONE
Brojčani podacivol. 9, br. 4, e95229
p-ISSN1932-6203
DOIhttps://doi.org/10.1371/journal.pone.0095229
URN:NBNurn:nbn:hr:105:384911
Datum objave publikacije2014-04-18
URL dokumentahttp://doi.org/10.1371/journal.pone.0095229
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 08:07:32