prikaz prve stranice dokumenta Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus
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Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus
Diabetes Research and Clinical Practice, 116 (2016); 111-116. https://doi.org/10.1016/j.diabres.2016.04.042
Duvnjak, Lea; Tomić, Martina; Blaslov, Kristina; Vučković Rebrina, Sandra

Citirajte ovaj rad

Duvnjak, L., Tomić, M., Blaslov, K. i Vučković Rebrina, S. (2016). Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus. Diabetes Research and Clinical Practice, 116., 111-116. doi: 10.1016/j.diabres.2016.04.042

Duvnjak, Lea, et al. "Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus." Diabetes Research and Clinical Practice, vol. 116, 2016, str. 111-116. https://doi.org/10.1016/j.diabres.2016.04.042

Duvnjak, Lea, Martina Tomić, Kristina Blaslov i Sandra Vučković Rebrina. "Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus." Diabetes Research and Clinical Practice 116 (2016): 111-116. https://doi.org/10.1016/j.diabres.2016.04.042

Duvnjak, L., et al. (2016) 'Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus', Diabetes Research and Clinical Practice, 116, str. 111-116. doi: 10.1016/j.diabres.2016.04.042

Duvnjak L, Tomić M, Blaslov K, Vučković Rebrina S. Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus. Diabetes Research and Clinical Practice [Internet]. 06.2016. [pristupljeno 18.08.2024.];116:111-116. doi: 10.1016/j.diabres.2016.04.042

L. Duvnjak, M. Tomić, K. Blaslov i S. Vučković Rebrina, "Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus", Diabetes Research and Clinical Practice, vol. 116, str. 111-116, Lipanj 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:773517. [Citirano: 18.08.2024.]

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Podaci o radu
Naslov (engleski)Autonomic nervous system function assessed by conventional and spectral analysis might be useful in terms of predicting retinal deterioration in persons with type 1 diabetes mellitus
AutorLea Duvnjak
AutorMartina Tomić
AutorKristina Blaslov
AutorSandra Vučković Rebrina
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
AIMS: To determine whether cardiac autonomic dysfunction represents a risk factor for diabetic retinopathy (DR) development and progression in persons with type 1 diabetes mellitus (T1DM). ----- METHODS: The study comprised 154 normoalbuminuric persons with T1DM divided into two groups according to the DR presence: with and without DR. Cardiovascular autonomic functioning was measured at baseline using conventional and spectral analysis. Participants were re-examined for the DR presence 18months after. ----- RESULTS: The group with DR had longer disease duration compared to the group without DR (20 vrs 11.5years, p<0.001), heart rate coefficient of variation (HRV-CV) at rest and during deep breathing were lower in participants with DR (p=0.001 and 0.004), as well did spectral indices of HRV: low frequency (LF) band, high frequency (HF) band (p=0.003 and 0.022) while LF/HF ratio indicating sympathovagal balance was higher (p=0.037). No difference in glycaemic control or blood pressure value were observed. Twenty-one (13.36%) participants developed non proliferative DR or progressed to proliferative DR. Cox proportional regression showed that the 18months risk from retinal deterioration was reduced by 33.4% by each increase in the HRV-CV of 1%, 12.7% for the same HRV-CV increase during deep breathing while LF band of 1ms(2) results in 8.6% risk reduction. ----- CONCLUSIONS: This study provides evidence that DR should not be considered merely a metabolic control manifestation and that HRV-CV as well as spectral indices of HRV might serve as a practical tool to identify a subgroup of T1DM patients with higher risk of retinal deterioration.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaDiabetes Research and Clinical Practice
Brojčani podacivol. 116, str. 111-116
p-ISSN0168-8227
DOIhttps://doi.org/10.1016/j.diabres.2016.04.042
URN:NBNurn:nbn:hr:105:773517
Datum objave publikacije2016-06
URL dokumentahttps://doi.org/10.1016/j.diabres.2016.04.042
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 08:55:41