prikaz prve stranice dokumenta Serum concentration of HDL particles predicts mortality in acute heart failure patients
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Serum concentration of HDL particles predicts mortality in acute heart failure patients
Scientific Reports, 7 (2017); 46642. https://doi.org/10.1038/srep46642
Potočnjak, Ines; Degoricija, Vesna; Trbušić, Matias; Pregartner, Gudrun; Berghold, Andrea; Marsche, Gunther; Frank, Saša

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Potočnjak, I., Degoricija, V., Trbušić, M., Pregartner, G., Berghold, A., Marsche, G. i Frank, S. (2017). Serum concentration of HDL particles predicts mortality in acute heart failure patients. Scientific Reports, 7., 46642. doi: 10.1038/srep46642

Potočnjak, Ines, et al. "Serum concentration of HDL particles predicts mortality in acute heart failure patients." Scientific Reports, vol. 7, 2017, str. 46642. https://doi.org/10.1038/srep46642

Potočnjak, Ines, Vesna Degoricija, Matias Trbušić, Gudrun Pregartner, Andrea Berghold, Gunther Marsche i Saša Frank. "Serum concentration of HDL particles predicts mortality in acute heart failure patients." Scientific Reports 7 (2017): 46642. https://doi.org/10.1038/srep46642

Potočnjak, I., et al. (2017) 'Serum concentration of HDL particles predicts mortality in acute heart failure patients', Scientific Reports, 7, str. 46642. doi: 10.1038/srep46642

Potočnjak I, Degoricija V, Trbušić M, Pregartner G, Berghold A, Marsche G, i sur.. Serum concentration of HDL particles predicts mortality in acute heart failure patients. Scientific Reports [Internet]. 18.04.2017. [pristupljeno 20.12.2024.];7:46642. doi: 10.1038/srep46642

I. Potočnjak, et al., "Serum concentration of HDL particles predicts mortality in acute heart failure patients", Scientific Reports, vol. 7, str. 46642, Travanj 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:883691. [Citirano: 20.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:883691
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Naslov (engleski)Serum concentration of HDL particles predicts mortality in acute heart failure patients
AutorInes Potočnjak
AutorVesna Degoricija
AutorMatias Trbušić
AutorGudrun Pregartner
AutorAndrea Berghold
AutorGunther Marsche
AutorSaša Frank
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Clinical studies have shown that assessing circulating concentrations of high-density lipoprotein (HDL) particles by nuclear magnetic resonance (NMR) spectroscopy is superior to HDL-cholesterol in predicting cardiovascular risk. We tested the hypothesis that circulating concentrations of HDL particles predict 3-month mortality of patients with acute heart failure (AHF). Out of 152 included patients, 52% were female, additionally the mean patient age was 75.2 ± 10.3 years, and three-month mortality was 27%. Serum lipoprotein profile at admission was determined by NMR spectroscopy. Univariate logistic regression analyses revealed a significant inverse association of total (odds ratio (OR) 0.38 per 1-SD increase, 95% confidence interval (CI) 0.23-0.60, p < 0.001) and small HDL particle concentrations (OR 0.35 per 1-SD increase, 95% CI 0.19-0.60, p < 0.001) with 3-month mortality, whereas concentrations of large HDL particles (p = 0.353) or HDL-cholesterol (p = 0.107) showed no significant association. After adjustment for age, sex, mean arterial pressure, low-density lipoprotein cholesterol, glomerular filtration rate, urea, and N-terminal pro-brain natriuretic peptide, both the total and small HDL particle concentrations remained significantly associated with 3-month mortality. Based on our results, we conclude that total and small HDL particle concentrations strongly and independently predict 3-month mortality in AHF patients.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaScientific Reports
Brojčani podacivol. 7, str. 46642
p-ISSN2045-2322
DOIhttps://doi.org/10.1038/srep46642
URN:NBNurn:nbn:hr:105:883691
Datum objave publikacije2017-04-18
URL dokumentahttps://doi.org/10.1038/srep46642
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 09:10:57