prikaz prve stranice dokumenta Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia
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Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia
Scientific Reports, 8 (2018), 1; 6113. https://doi.org/doi:10.1038/s41598-018-24446-4
Višković, Klaudija; Židovec Lepej, Snježana; Gorenec, Ana; Grgić, Ivana; Lukas, Davorka; Zekan, Šime; Dragobratović, Anja; Trupković, Maja; Begovac, Josip

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Višković, K., Židovec Lepej, S., Gorenec, A., Grgić, I., Lukas, D., Zekan, Š. ... Begovac, J. (2018). Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia. Scientific Reports, 8. (1), 6113. doi: doi:10.1038/s41598-018-24446-4

Višković, Klaudija, et al. "Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia." Scientific Reports, vol. 8, br. 1, 2018, str. 6113. https://doi.org/doi:10.1038/s41598-018-24446-4

Višković, Klaudija, Snježana Židovec Lepej, Ana Gorenec, Ivana Grgić, Davorka Lukas, Šime Zekan, Anja Dragobratović, Maja Trupković i Josip Begovac. "Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia." Scientific Reports 8, br. 1 (2018): 6113. https://doi.org/doi:10.1038/s41598-018-24446-4

Višković, K., et al. (2018) 'Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia', Scientific Reports, 8(1), str. 6113. doi: doi:10.1038/s41598-018-24446-4

Višković K, Židovec Lepej S, Gorenec A, Grgić I, Lukas D, Zekan Š, i sur.. Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia. Scientific Reports [Internet]. 17.04.2018. [pristupljeno 09.10.2024.];8(1):6113. doi: doi:10.1038/s41598-018-24446-4

K. Višković, et al., "Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia", Scientific Reports, vol. 8, br. 1, str. 6113, Travanj 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:982107. [Citirano: 09.10.2024.]

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Naslov (engleski)Cardiovascular markers of inflammation and serum lipid levels in HIV-infected patients with undetectable viremia
AutorKlaudija Višković
AutorSnježana Židovec Lepej
AutorAna Gorenec
AutorIvana Grgić
AutorDavorka Lukas
AutorŠime Zekan
AutorAnja Dragobratović
AutorMaja Trupković
AutorJosip Begovac
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Patients successfully treated for HIV infection still have an increased risk for cardiovascular morbidity and mortality, which might be related not only to traditional risks, but also to inflammation and dyslipidemia. We examined the relationship of serum lipid levels with plasma biomarkers of inflammation using a composite inflammatory burden score (IBS) based on individual (>75th percentile) measurements from the following seven markers: CD40L, tPA, MCP-1, IL-8, IL-6, hCRP and P-selectin. IBS was categorized as 0 (none of the biomarkers >75th percentile), 1, 2 and 3 or more scores. Correlations between the IBS and lipid parameters were examined by ordered logistic regression proportional odds models to estimate the odds of more elevated biomarkers. 181 male patients with undetectable HIV-viremia were included into the study. In the multivariate model, a one-unit increase (mmol/L) of total cholesterol and triglycerides was associated with a 1.41-fold (95% CI, 1.13-1.76) and 1.37-fold (95% CI, 1.18-1.60) increased odds of having a greater IBS, respectively. Those with an IBS score ≥1 compared to none had 2.14 (95% CI, 1.43-3.20) higher odds of having a one-unit increased total cholesterol/HDL-cholesterol ratio. In successfully treated HIV-infected persons dyslipidemia was associated with inflammation.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaScientific Reports
Brojčani podacivol. 8, br. 1, str. 6113
p-ISSN2045-2322
DOIhttps://doi.org/doi:10.1038/s41598-018-24446-4
URN:NBNurn:nbn:hr:105:982107
Datum objave publikacije2018-04-17
URL dokumentahttp://doi.org/10.1038/s41598-018-24446-4
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:19:02