Unnecessary prescribing of antibiotics to healthy/asymptomatic school-age carriers of potentially pathogenic bacteria

Znanstveni rad - Izvorni znanstveni rad

• Autor: Mirjana Kostić
• Autor: Vladimir Bedeković
• Autor: Biserka Bastijančić-Kokić
• Autor: Tomislav Lauc
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti

Sažetak (engleski)

Objectives: To re-draw attention to the unnecessary prescribing of antibiotics.
----- Methods: We monitored nasopharyngeal colonization by 3 potentially pathogenic bacteria, Streptococcus pyogenes, Streptococcus pneumoniae, and Haemophilus influenzae type b in 81 children between the ages of 6 and 7 years who attended the same primary school. The children's health status was also monitored, without using antimicrobial treatment for healthy/asymptomatic carriers. Nasopharyngeal swabs were collected on 6 occasions during autumn months, from mid-September to mid-December 2016. The children who fell ill during the study were treated at the Ear, Nose and Throat Clinic, Sisters of Mercy University Hospital Center, Zagreb, Croatia.
----- Results: Four hundred and sixty-three nasopharyngeal swabs were collected. Each child had at least one positive swab result. Bacterial colonization with Streptococcus pyogenes had the highest colonization rate. During the study, 83% of the children were healthy/asymptomatic carriers with no clinical signs of disease, while 17% became ill. The statistical results showed that the increase in all examined bacteria was statistically significant.
----- Conclusions: Our study results showed that positive bacterial findings in nasopharyngeal swabs from clinically healthy carriers were not an indication for antibiotic therapy.

• Ključne riječi (engleski): Anti-Bacterial Agents / adverse effects; Carrier State / microbiology; Child; Female; Haemophilus influenzae type b / isolation & purification; Haemophilus influenzae type b / pathogenicity; Humans; Inappropriate Prescribing / prevention & control; Male; Nasopharynx / microbiology; Schools; Seasons; Streptococcus pneumoniae / isolation & purification; Streptococcus pneumoniae / pathogenicity; Streptococcus pyogenes / isolation & purification; Streptococcus pyogenes / pathogenicity; Time Factors
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Saudi Medical Journal
• Brojčani podaci: vol. 40, br. 4, str. 405-408
• p-ISSN: 0379-5284
• DOI: https://doi.org/10.15537/smj.2019.4.24004
• URN:NBN: urn:nbn:hr:105:452792
• Datum objave publikacije: 2019-04
• URL dokumenta: http://doi.org/10.15537/smj.2019.4.24004
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2024-03-28 10:35:54