prikaz prve stranice dokumenta Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?
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Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?
Virchows Archiv, 456 (2010), 1; 85-89. https://doi.org/10.1007/s00428-009-0868-x
Demirović, Alma; Cesarec, Sanja; Spajić, Borislav; Tomas, Davor; Bulimbašić, Stela; Milošević, Milan; Marušić, Zlatko; Krušlin, Božo

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Demirović, A., Cesarec, S., Spajić, B., Tomas, D., Bulimbašić, S., Milošević, M. ... Krušlin, B. (2010). Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?. Virchows Archiv, 456. (1), 85-89. doi: 10.1007/s00428-009-0868-x

Demirović, Alma, et al. "Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?." Virchows Archiv, vol. 456, br. 1, 2010, str. 85-89. https://doi.org/10.1007/s00428-009-0868-x

Demirović, Alma, Sanja Cesarec, Borislav Spajić, Davor Tomas, Stela Bulimbašić, Milan Milošević, Zlatko Marušić i Božo Krušlin. "Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?." Virchows Archiv 456, br. 1 (2010): 85-89. https://doi.org/10.1007/s00428-009-0868-x

Demirović, A., et al. (2010) 'Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?', Virchows Archiv, 456(1), str. 85-89. doi: 10.1007/s00428-009-0868-x

Demirović A, Cesarec S, Spajić B, Tomas D, Bulimbašić S, Milošević M, i sur.. Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?. Virchows Archiv [Internet]. 01.2010. [pristupljeno 07.10.2024.];456(1):85-89. doi: 10.1007/s00428-009-0868-x

A. Demirović, et al., "Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?", Virchows Archiv, vol. 456, br. 1, str. 85-89, Siječanj 2010. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:522212. [Citirano: 07.10.2024.]

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Naslov (engleski)Can renal oncocytoma be distinguished from chromophobe renal cell carcinoma by the presence of fibrous capsule?
AutorAlma Demirović
AutorSanja Cesarec
AutorBorislav Spajić
AutorDavor Tomas
AutorStela Bulimbašić
AutorMilan Milošević
AutorZlatko Marušić
AutorBožo Krušlin
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The most important differential diagnosis of chromophobe renal cell carcinoma (CRCC) is renal oncocytoma. Due to overlapping morphological characteristics of renal oncocytoma and CRCC, particularly its eosinophilic variant, making a correct diagnosis can be challenging. To date, no data are available on the presence of the tumor fibrous capsule as a diagnostic feature in differentiating these tumors. The main purpose of this study was to establish the presence and compare the thickness of the tumor fibrous capsule between two tumor groups. A total of 37 tumors--18 cases of CRCC (three eosinophilic and 15 classic) and 19 cases of renal oncocytoma--were analyzed. Four slides of each tumor stained with hematoxylin and eosin were first scanned at low-power magnification (x40) to assess the presence of the capsule. If present, the capsule was measured in three different thickest areas at higher magnification (x200). The mean value of capsule thickness was calculated and taken into consideration. The capsule was present in 12 (66.7%) cases of CRCCs and in only two (10.5%) cases of renal oncocytomas. Statistical analysis showed significant difference between the presence of fibrous capsule in these two observed tumor groups (P = 0.001). Average thickness of capsule in CRCCs was 337.7 microm, and 115.4 microm in renal oncocytomas, but the median was not statistically significant (P = 0.198). Studies with a larger number of cases are needed to conclude if this characteristic could be a low-cost, reliable microscopic feature in differentiating between CRCC and renal oncocytoma.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaVirchows Archiv
Brojčani podacivol. 456, br. 1, str. 85-89
p-ISSN0945-6317
DOIhttps://doi.org/10.1007/s00428-009-0868-x
URN:NBNurn:nbn:hr:105:522212
Datum objave publikacije2010-01
URL dokumentahttps://doi.org/10.1007/s00428-009-0868-x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 12:00:10