Paginacija
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The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds
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Viviana Wahl Vacuum assisted closure therapy was developed for the needs of plastic surgery in the 90s. Primarily used for the treatment of patients with large chronic wounds, the usage nowadays extends to area of medicine and veterinary, for all types of large, chronic and infected wounds, where increased drainage of the exudate and help with wound closure is needed. Vacuum assisted closure therapy uses sub-atmospheric pressure between 50 and 200 mmHg which facilitates drainage of fluids, reduces...
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The outcome of assisted reproductive techniques in women with autoimmune disorders
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Lital Sarit Abadi Infertility is estimated to affect about 8-12% of reproductive-aged couples across the globe. It is a clinical manifestation of different etiological factors, which may affect males, females, or both. The distribution of the most common causes affecting female fertility varies among different countries; and in developed countries it usually involves disorders of ovulation, endometriosis, pelvic adhesions, fallopian tube blockage, as well as hyperprolactinemia. Autoimmune diseases may also...
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The prevalence of cardiovascular risks in HIV-infected persons in care in Croatia in 2015
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Ivan Raymond Marius Desbordes Aim:This review will aim at considering the prevalence of cardiovascular risks among the HIV-infected population undergoing ART therapy in Croatia: Cardiovascular diseases are now among the most common causes of mortality in people living with HIV. We will see for which reasons people living with HIV appear to have an elevated risk for cardiovascular diseases. ----- Method: A cross-sectional analysis of 310 consecutive HIV infected patients seen during a routine clinical visit aged 40 to 79...
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The relationship between doctor's health and safe patient care
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Amanda Josephine Lam Safe patient care is an aspect of healthcare that is becoming increasingly recognized by the world’s healthcare professionals as a crucial component of optimal patient outcome. Patient safety places emphasis on a physician’s duty to report, analyze and prevent medical errors. Safe patient care is highly dependent upon a competent and functioning physician. The psychological
and physical health of a doctor is vital in ensuring safe patient outcome. Today’s medical professionals have...
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The role of 3D computing planning in maxillofacial surgery
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Alban Gecaj The role of 3D computing in reconstructive surgery is still not clearly established, yet the advancements of virtual surgical planning (VSP) and its implementation for various indications is slowly elucidating its purpose.
VSP consist of multiple techniques which are being used to complement surgery in its planning stage as well as during it. Such techniques can be divided into computer assisted surgery (CAS), computer assisted design (CAD) and computer assisted manufacturing (CAM)....
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The role of DNA methylation in human spermatogenesis
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Inbar Shafran What is the story behind the term “germ cell epigenetics”, what can we learn from the changes in methylation during gametogenesis, and how could it be put to good use? This thesis aims to explain how changes in the DNA methylation affects the development of primordial cells into mature sperm.
Methylation is the epigenetic process controlling what genes will be expressed and what genes will be silenced. Epigenetics can be viewed as the environmental inheritance we get from our...
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The role of adipokines in polycystic ovary syndrome
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Maja Šikić Polycystic ovary syndrome (PCOS) is an exceedingly complex endocrine, reproductive
and metabolic disorder of a diverse and still unclear pathogenesis. PCOS affects
approximately 10% of women of reproductive age and is considered one of the most
common endocrine and reproductive disturbances in its group (1)(2). The syndrome is
clinically characterised by oligo/anovulation and infertility, hirsutism and abdominal obesity
(3).
However, the absence of clearly defined causative factors and...
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The role of limosilactobacillus reuteri strains on human health
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Adam Bošnjak In recent years the human gastrointestinal microbiota has proven to play a critical role in host health and disease. The majority of human microbiota resides in the large intestine and is composed of a diverse array of microorganisms, including bacteria, fungi, and archaea. Among these, Limosilactobacillus reuteri (formerly known as Lactobacillus reuteri), a gram-positive, heterofermentative lactic acid bacterium has gained attention as a probiotic due to its potential health benefits....
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The role of platelet tests in detection of clopidogrel hyper-response after percutaneous coronary intervention
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Michael John Grašić Clopidogrel is a PY212 antiplatelet medication which was shown to reduce mortality in patients post PCI. A percentage of the population has a resultant low platelet reactivity (LPR) or high platelet reactivity (HPR) while taking Clopidogrel. There is a connection between the LPR and increased rates of bleeding events as well as a connection between HPR and increased rates of ST events. We will examine bleeding avoidant strategies (BAS) which may be implemented to reduce bleeding event in...
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The role of the FaS/FasL apoptotic pathway on osteoclastogenesis in the mouse model of controlled tibial fractures
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Nina Lukač The Fas/FasL apoptotic system serves as a regulator of the immune system, but also has an influence on osteoclast survival and differentiation. The model of internally fixated controlled tibial fractures was used to evaluate its role on osteoclastogenesis in formation of new bone, as fracture healing serves as a model for embryonic skeletal development. The aim of this study was to evaluate the role of the apoptotic system on osteoclastogenesis in vivo, by evaluating the osteoclastogenic...
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The usage of antibiotics in bone surgery
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Patrick Julien Bernard Tschechne The discovery of antibiotics has drastically changed modern medicine and everyday human life. Even though extraordinary discoveries have been made perioperative infections are still commonly encountered in clinical practice. Deep infections such as septic arthritis, osteomyelitis and periprosthetic joint infections pose great difficulties to practising surgeons and increase the financial burden for health care systems across the globe. Multiple antibiotic regimens are commonly used where...
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The use of alternative vascular access in emergency care
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Máté Huba Huszár A variety of alternative emergency vascular access solutions have been tested and described in the literature. In cases of difficult intravenous access (DIVA) in emergency settings, intraosseous access (IO) has consistently been suggested by professional organisations as the most suitable alternative to peripheral venous catheters (PVC) due to its proven superiority. IO is the quickest and safest option when immediate intravenous access cannot be established.
This thesis, as a descriptive...
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