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In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes
Biomedicines, 12 (2024), 2; 381. https://doi.org/10.3390/biomedicines12020381
Bulum, Tomislav; Brkljačić, Neva; Tičinović Ivančić, Angelika; Čavlović, Maja; Prkačin, Ingrid; Tomić, Martina

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Bulum, T., Brkljačić, N., Tičinović Ivančić, A., Čavlović, M., Prkačin, I. i Tomić, M. (2024). In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes. Biomedicines, 12. (2). doi: 10.3390/biomedicines12020381

Bulum, Tomislav, et al. "In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes." Biomedicines, vol. 12, br. 2, 2024. https://doi.org/10.3390/biomedicines12020381

Bulum, Tomislav, Neva Brkljačić, Angelika Tičinović Ivančić, Maja Čavlović, Ingrid Prkačin i Martina Tomić. "In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes." Biomedicines 12, br. 2 (2024). https://doi.org/10.3390/biomedicines12020381

Bulum, T., et al. (2024) 'In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes', Biomedicines, 12(2). doi: 10.3390/biomedicines12020381

Bulum T, Brkljačić N, Tičinović Ivančić A, Čavlović M, Prkačin I, Tomić M. In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes. Biomedicines [Internet]. 07.02.2024. [pristupljeno 23.12.2024.];12(2). doi: 10.3390/biomedicines12020381

T. Bulum, N. Brkljačić, A. Tičinović Ivančić, M. Čavlović, I. Prkačin i M. Tomić, "In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes", Biomedicines, vol. 12, br. 2, Veljača 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:542841. [Citirano: 23.12.2024.]

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Podaci o radu
Naslov (engleski)In Association with Other Risk Factors, Smoking Is the Main Predictor for Lower Transcutaneous Oxygen Pressure in Type 2 Diabetes
AutorTomislav Bulum
AutorNeva Brkljačić
AutorAngelika Tičinović Ivančić
AutorMaja Čavlović
AutorIngrid Prkačin
AutorMartina Tomić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Type 2 diabetes mellitus (T2DM) significantly increases the risk of peripheral artery disease (PAD), and diabetes is the leading cause of nontraumatic amputations. This study investigated the risk factors for transcutaneous oxygen pressure (TcPO2) in T2DM, a noninvasive method to quantify skin oxygenation and the underlying microvascular circulation. The study included 119 T2DM patients (91 male/28 female). TcPO2 measurements were conducted with the Tina TCM4 Series transcutaneous monitor (Radiometer, Copenhagen, Sweden) and skin electrodes. Patients with TcPO2 < 40 mmHg were younger (p = 0.001), had significantly higher systolic blood pressure (SBP) (p = 0.023), glycated hemoglobin (HbA1c) (p = 0.013), fasting plasma glucose (fPG) (p = 0.038), total cholesterol (p = 0.006), LDL cholesterol (p = 0.004), and had more frequent smoking habits (p = 0.001) than those with TcPO2 ≥ 40 mmHg. The main predictors for the TcPO2 value (R2 = 0.211) obtained via stepwise regression analysis were age, smoking, SBP, HbA1c, fPG, and total and LDL cholesterol. Among all the listed predictors, smoking, HbA1c, and LDL cholesterol were found to be the most significant, with negative parameter estimates of −3.051310 (p = 0.0007), −2.032018 (p = 0.0003), and −2.560353 (p = 0.0046). The results of our study suggest that in association with other risk factors, smoking is the main predictor for lower TcPO2 in T2DM.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 12, br. 2, 381
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines12020381
URN:NBNurn:nbn:hr:105:542841
Datum objave publikacije2024-02-07
URL dokumentahttps://www.mdpi.com/2227-9059/12/2/381
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-11-13 14:47:57