prikaz prve stranice dokumenta Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices
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Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices
Diagnostics, 14 (2024), 7; 743. https://doi.org/10.3390/diagnostics14070743
Madir, Anita; Barišić Jaman, Mislav; Milošević, Marko; Dinjar Kujundžić, Petra; Grgurević, Ivica

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Madir, A., Barišić Jaman, M., Milošević, M., Dinjar Kujundžić, P. i Grgurević, I. (2024). Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices. Diagnostics, 14. (7). doi: 10.3390/diagnostics14070743

Madir, Anita, et al. "Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices." Diagnostics, vol. 14, br. 7, 2024. https://doi.org/10.3390/diagnostics14070743

Madir, Anita, Mislav Barišić Jaman, Marko Milošević, Petra Dinjar Kujundžić i Ivica Grgurević. "Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices." Diagnostics 14, br. 7 (2024). https://doi.org/10.3390/diagnostics14070743

Madir, A., et al. (2024) 'Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices', Diagnostics, 14(7). doi: 10.3390/diagnostics14070743

Madir A, Barišić Jaman M, Milošević M, Dinjar Kujundžić P, Grgurević I. Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices. Diagnostics [Internet]. 30.03.2024. [pristupljeno 13.03.2025.];14(7). doi: 10.3390/diagnostics14070743

A. Madir, M. Barišić Jaman, M. Milošević, P. Dinjar Kujundžić i I. Grgurević, "Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices", Diagnostics, vol. 14, br. 7, Ožujak 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:964347. [Citirano: 13.03.2025.]

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Podaci o radu
Naslov (engleski)Improved Applicability and Diagnostic Accuracy of the Novel Spleen-Dedicated Transient Elastography Device for High-Risk Esophageal Varices
AutorAnita Madir
AutorMislav Barišić Jaman
AutorMarko Milošević
AutorPetra Dinjar Kujundžić
AutorIvica Grgurević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Spleen stiffness measurement (SSM) by transient elastography (TE) has been repeatedly demonstrated as the reliable way to rule out the presence of high-risk esophageal varices (HRV). We aimed to evaluate and compare novel vs. standard TE-SSM module performance in diagnosing HRV in patients with compensated advanced chronic liver disease (cACLD). This retrospective study included patients with cACLD; blood data, upper digestive endoscopy performed within 3 months of TE, SSM@50Hz and SSM@100Hz were collected. Overall, 112 patients with cACLD were analyzed (75.9% males, average age of 66, 43.7% alcohol-related chronic liver disease, 22.3% metabolic-associated steatotic liver disease, 6.2% viral hepatitis). Reliable SSM was possible in 80.3% and 93.8% of patients by using SSM@50Hz and SSM@100Hz probe, respectively. At the cut-off 41.8 kPa and 40.9 kPa (Youden), SSM@50Hz and SSM@100Hz had AUROCs of 0.746 and 0.752, respectively, for diagnosing HRV (p = 0.71). At the respective cut-offs, sensitivities for HRV were 92.9% and 100%, resulting in misclassification rates of 7.1% and 0% by using SSM@50Hz and SSM@100Hz. SSM reliably excludes HRV in cACLD patients, with measurements below 41 kPa potentially avoiding EGD in around 50% of cases, with minimal risk of HRV omission. SSM@100Hz demonstrated less measurement failures and no HRV misclassification.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 14, br. 7, 743
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics14070743
URN:NBNurn:nbn:hr:105:964347
Datum objave publikacije2024-03-30
URL dokumentahttps://www.mdpi.com/2075-4418/14/7/743
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-03-12 13:47:49