prikaz prve stranice dokumenta Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome
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Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome
Biomedicines, 12 (2024), 9; 1972. https://doi.org/10.3390/biomedicines12091972
Klobučar, Iva; Habisch, Hansjörg; Klobučar, Lucija; Trbušić, Matias; Pregartner, Gudrun; Berghold, Andrea; Kostner, Gerhard M.; Scharnagl, Hubert; Madl, Tobias; Frank, Saša; Degoricija, Vesna

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Klobučar, I., Habisch, H., Klobučar, L., Trbušić, M., Pregartner, G., Berghold, A. ... Degoricija, V. (2024). Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome. Biomedicines, 12. (9). doi: 10.3390/biomedicines12091972

Klobučar, Iva, et al. "Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome." Biomedicines, vol. 12, br. 9, 2024. https://doi.org/10.3390/biomedicines12091972

Klobučar, Iva, Hansjörg Habisch, Lucija Klobučar, Matias Trbušić, Gudrun Pregartner, Andrea Berghold, Gerhard M. Kostner, et al. "Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome." Biomedicines 12, br. 9 (2024). https://doi.org/10.3390/biomedicines12091972

Klobučar, I., et al. (2024) 'Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome', Biomedicines, 12(9). doi: 10.3390/biomedicines12091972

Klobučar I, Habisch H, Klobučar L, Trbušić M, Pregartner G, Berghold A, i sur.. Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome. Biomedicines [Internet]. 01.09.2024. [pristupljeno 20.03.2025.];12(9). doi: 10.3390/biomedicines12091972

I. Klobučar, et al., "Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome", Biomedicines, vol. 12, br. 9, Rujan 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:290616. [Citirano: 20.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:290616
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Naslov (engleski)Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome
AutorIva Klobučar
AutorHansjörg Habisch
AutorLucija Klobučar
AutorMatias Trbušić
AutorGudrun Pregartner
AutorAndrea Berghold
AutorGerhard M. Kostner
AutorHubert Scharnagl
AutorTobias Madl
AutorSaša Frank
AutorVesna Degoricija
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The strong associations between the serum levels of adiponectin and the lipoprotein subclasses observed in healthy subjects are much weaker in patients with metabolic syndrome (MS). However, the impact of sex on these associations remained unexplored. Therefore, in the present study, we examined associations between adiponectin and the lipoprotein subclasses, analyzed by nuclear magnetic resonance spectroscopy, separately in healthy females and males, as well as in females and males with MS. We observed negative correlations between adiponectin and VLDL, IDL, and small-dense LDL in healthy males, but neither in healthy females nor in females or males with MS. Additionally, adiponectin was positively correlated with some HDL subclasses in healthy males and females with MS, but not in healthy females or males with MS. Adjusting for age and either body mass index, waist circumference, C-reactive protein, or interleukin-6 weakened the associations between adiponectin and VLDL and IDL but not small-dense LDL. The adjustment weakened the associations between adiponectin and HDL in healthy males but not in females with MS. Based on our results, we conclude that sex and the presence of MS are strong determinants of the associations between adiponectin and serum lipoproteins and that the complex regulatory network comprising adiponectin and other molecular players involved in the regulation of lipoprotein metabolism is primarily operative in healthy males and females with MS.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 12, br. 9, 1972
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines12091972
URN:NBNurn:nbn:hr:105:290616
Datum objave publikacije2024-09-01
URL dokumentahttps://www.mdpi.com/2227-9059/12/9/1972
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-03-20 08:28:17