prikaz prve stranice dokumenta Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients
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Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients
Journal of Clinical Medicine, 13 (2024), 13; 3716. https://doi.org/10.3390/jcm13133716
Atić, Armin; Matijašević Škerlj, Jasmina; Jurić, Ivana; Katalinić, Lea; Furić Čunko, Vesna; Kljajić, Marina; Sabljić, Zoran; Jelaković, Bojan; Bašić-Jukić, Nikolina

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Atić, A., Matijašević Škerlj, J., Jurić, I., Katalinić, L., Furić Čunko, V., Kljajić, M. ... Bašić Jukić, N. (2024). Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients. Journal of Clinical Medicine, 13. (13). doi: 10.3390/jcm13133716

Atić, Armin, et al. "Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients." Journal of Clinical Medicine, vol. 13, br. 13, 2024. https://doi.org/10.3390/jcm13133716

Atić, Armin, Jasmina Matijašević Škerlj, Ivana Jurić, Lea Katalinić, Vesna Furić Čunko, Marina Kljajić, Zoran Sabljić, Bojan Jelaković i Nikolina Bašić Jukić. "Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients." Journal of Clinical Medicine 13, br. 13 (2024). https://doi.org/10.3390/jcm13133716

Atić, A., et al. (2024) 'Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients', Journal of Clinical Medicine, 13(13). doi: 10.3390/jcm13133716

Atić A, Matijašević Škerlj J, Jurić I, Katalinić L, Furić Čunko V, Kljajić M, i sur.. Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients. Journal of Clinical Medicine [Internet]. 26.06.2024. [pristupljeno 11.04.2025.];13(13). doi: 10.3390/jcm13133716

A. Atić, et al., "Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients", Journal of Clinical Medicine, vol. 13, br. 13, Lipanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:427297. [Citirano: 11.04.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:427297
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Podaci o radu
Naslov (engleski)Factors Associated with Hyperpolypharmacy and Complex Medication Regimens in Kidney Transplant Recipients
AutorArmin Atić
AutorJasmina Matijašević Škerlj
AutorIvana Jurić
AutorLea Katalinić
AutorVesna Furić Čunko
AutorMarina Kljajić
AutorZoran Sabljić
AutorBojan Jelaković
AutorNikolina Bašić-Jukić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Kidney transplantation is considered the best modality for renal replacement therapy. The use of immunosuppressive therapy and pre-existing and newly developed comorbidities predispose these patients to the use of a large number of medications. (Hyper)polypharmacy is associated with worse adherence and negative outcomes. This study aims to explore the factors correlated with hyperpolypharmacy and complex medication regimens in kidney transplant recipients. Methods: This is a cross-sectional study of outpatient kidney transplant recipients. Collected data include demographic data, complete chronic medication lists, medical history, and graft function. Linear and logistic regression were used to identify factors associated with hyperpolypharmacy and complex medication regimens. Medication regimen complexity was quantified by the Medication Regimen Complexity Index (MRCI). Results: Overall, 224 kidney transplant recipients were included, with an average time since transplantation of 8 years. Hyperpolypharmacy was present in more than two-thirds of patients; the average number of different medications was 12; and the mean MRCI score was 21.4, ranging from 6 to 50. Hypertension was almost universally present, while other frequently prescribed medication groups were hypolipemics, medication for bone-mineral metabolism disorders, gout, and antihyperglycemics. Conclusions: Factors independently associated with hyperpolypharmacy and complex medication regimens were found to be age and graft function. Studies investigating interventions aimed at reducing medication complexity and increasing adherence should focus on older patients with worse graft function.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 13, br. 13, 3716
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm13133716
URN:NBNurn:nbn:hr:105:427297
Datum objave publikacije2024-06-26
URL dokumentahttps://www.mdpi.com/2077-0383/13/13/3716
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-04-11 07:30:58