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Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)
International Journal of Infectious Diseases, 89 (2019); 3-9. https://doi.org/10.1016/j.ijid.2019.09.008
Vrdoljak, Maja; Gužvinec, Marija; Trkulja, Vladimir; Butić, Iva; Ivić, Ivo; Krželj, Vjekoslav; Tonkić, Marija; Hegeduš Jungvirth, Marija; Payerl Pal, Marina; Tešović, Goran

Citirajte ovaj rad

Vrdoljak, M., Gužvinec, M., Trkulja, V., Butić, I., Ivić, I., Krželj, V. ... Tešović, G. (2019). Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014). International Journal of Infectious Diseases, 89., 3-9. doi: 10.1016/j.ijid.2019.09.008

Vrdoljak, Maja, et al. "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)." International Journal of Infectious Diseases, vol. 89, 2019, str. 3-9. https://doi.org/10.1016/j.ijid.2019.09.008

Vrdoljak, Maja, Marija Gužvinec, Vladimir Trkulja, Iva Butić, Ivo Ivić, Vjekoslav Krželj, Marija Tonkić, Marija Hegeduš Jungvirth, Marina Payerl Pal i Goran Tešović. "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)." International Journal of Infectious Diseases 89 (2019): 3-9. https://doi.org/10.1016/j.ijid.2019.09.008

Vrdoljak, M., et al. (2019) 'Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)', International Journal of Infectious Diseases, 89, str. 3-9. doi: 10.1016/j.ijid.2019.09.008

Vrdoljak M, Gužvinec M, Trkulja V, Butić I, Ivić I, Krželj V, i sur.. Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014). International Journal of Infectious Diseases [Internet]. 12.2019. [pristupljeno 08.11.2024.];89:3-9. doi: 10.1016/j.ijid.2019.09.008

M. Vrdoljak, et al., "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)", International Journal of Infectious Diseases, vol. 89, str. 3-9, Prosinac 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:477113. [Citirano: 08.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:477113
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Podaci o radu
Naslov (engleski)Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)
AutorMaja Vrdoljak
AutorMarija Gužvinec
AutorVladimir Trkulja
AutorIva Butić
AutorIvo Ivić
AutorVjekoslav Krželj
AutorMarija Tonkić
AutorMarija Hegeduš Jungvirth
AutorMarina Payerl Pal
AutorGoran Tešović
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INFEKTOLOGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA TEMELJNU I KLINIČKU FARMAKOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
Objectives: Rotavirus is the major cause of severe diarrhea in young children worldwide. In countries like Croatia, where rotavirus vaccine has not been introduced in the national immunization program, prospective surveillance is necessary to establish the diversity of rotavirus strains. The aim of this study was to describe the prevalence and geographical distribution of rotavirus strains in Croatia and to detect the possible emergence of novel strains. ----- Methods: The study was conducted among children ≤5 years of age with acute gastroenteritis at three hospitals located in different geographical regions of Croatia, during the years 2012 to 2014. Rotavirus was detected in stools using an immunochromatographic assay and then sent for further molecular analysis. ----- Results: Genotyping of 822 rotaviruses showed that the predominant circulating strain was G1P[8] (61.9%), followed by G2P[4] (19.5%), G1P[4] (3.9%), and G3P[8] (2.9%). A high prevalence of reassortants among common human rotavirus genotypes was detected (7.7%). Possible zoonotic reassortants were found, including G8 and G6 strains. The latter is described for the first time in Croatia. ----- Conclusions: This study represents pre-vaccination data that are important for decisions regarding immunization strategies in Croatia. The high prevalence of 'common' rotavirus strains circulating in Croatia may advocate for rotavirus vaccine introduction, but further surveillance is necessary to monitor the possible emergence of novel genotypes.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Infectious Diseases
Brojčani podacivol. 89, str. 3-9
p-ISSN1201-9712
e-ISSN1878-3511
DOIhttps://doi.org/10.1016/j.ijid.2019.09.008
URN:NBNurn:nbn:hr:105:477113
Datum objave publikacije2019-12
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S1201971219303704
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2021-03-09 08:39:23