prikaz prve stranice dokumenta Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
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Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
Archives of Gynecology and Obstetrics, 301 (2020), 5; 1227-1233. https://doi.org/10.1007/s00404-020-05522-5
Mikuš, Mislav; Benco, Nikolina; Matak, Luka; Planinić, Pavao; Ćorić, Mario; Lovrić, Helena; Radošević, Velena; Puževski, Tomislav; Bajt, Mirna; Vujić, Goran

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Mikuš, M., Benco, N., Matak, L., Planinić, P., Ćorić, M., Lovrić, H. ... Vujić, G. (2020). Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center. Archives of Gynecology and Obstetrics, 301. (5), 1227-1233. doi: 10.1007/s00404-020-05522-5

Mikuš, Mislav, et al. "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center." Archives of Gynecology and Obstetrics, vol. 301, br. 5, 2020, str. 1227-1233. https://doi.org/10.1007/s00404-020-05522-5

Mikuš, Mislav, Nikolina Benco, Luka Matak, Pavao Planinić, Mario Ćorić, Helena Lovrić, Velena Radošević, Tomislav Puževski, Mirna Bajt i Goran Vujić. "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center." Archives of Gynecology and Obstetrics 301, br. 5 (2020): 1227-1233. https://doi.org/10.1007/s00404-020-05522-5

Mikuš, M., et al. (2020) 'Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center', Archives of Gynecology and Obstetrics, 301(5), str. 1227-1233. doi: 10.1007/s00404-020-05522-5

Mikuš M, Benco N, Matak L, Planinić P, Ćorić M, Lovrić H, i sur.. Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center. Archives of Gynecology and Obstetrics [Internet]. 05.2020. [pristupljeno 11.04.2024.];301(5):1227-1233. doi: 10.1007/s00404-020-05522-5

M. Mikuš, et al., "Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center", Archives of Gynecology and Obstetrics, vol. 301, br. 5, str. 1227-1233, Svibanj 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:015670. [Citirano: 11.04.2024.]

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Naslov (engleski)Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center
AutorMislav Mikuš
AutorNikolina Benco
AutorLuka Matak
AutorPavao Planinić
AutorMario Ćorić
AutorHelena Lovrić
AutorVelena Radošević
AutorTomislav Puževski
AutorMirna Bajt
AutorGoran Vujić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA GINEKOLOGIJU I OPSTETRICIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Purpose: To describe a case series of patients with malignant ovarian germ cell tumors (MOGCT) treated exclusively with fertility-sparing surgery (FSS) with or without adjuvant chemotherapy. ----- Methods: We retrospectively reviewed the records of 27 patients with MOGCT treated in the Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Croatia, between January 2009 and July 2019. ----- Results: The median age at diagnosis was 22 years, and the main symptom was abdominal distension (57.0%). The most prevalent histological subtype was immature teratoma (n = 13, 48.1%). Twenty-three patients (85.2%) had laparotomy and 4 (14.8%) had laparoscopy, without conversions. Lymphadenectomy was performed in 16 (59.3%) patients, with 184 removed lymph nodes, and omentectomy was performed in 19 (70.4%) patients. The rate of chemotherapy administration was 81.5%. The follow-up length ranged between 6.30 and 115.1 months (median: 49.60 months). No patient experienced tumor recurrence. The rate of complete gross resection was 100%. At the time of analysis, all patients were alive and disease free. Fifty percent of patients who actively tried to conceive after FSS became pregnant, with 12 deliveries. ----- Conclusion: This study suggests that FSS is a safe treatment option for MOGCT, regardless of tumor stage and histological type.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaArchives of Gynecology and Obstetrics
Brojčani podacivol. 301, br. 5, str. 1227-1233
p-ISSN0932-0067
e-ISSN1432-0711
DOIhttps://doi.org/10.1007/s00404-020-05522-5
URN:NBNurn:nbn:hr:105:015670
Datum objave publikacije2020-05
URL dokumentahttp://link.springer.com/10.1007/s00404-020-05522-5
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Datum isteka embarga: 2021-06-01
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2021-04-21 14:02:44