prikaz prve stranice dokumenta Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience
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Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience
Clinical Neurology and Neurosurgery, 201 (2021); 106426. https://doi.org/10.1016/j.clineuro.2020.106426
Bujan Kovač, Andreja; Petelin Gadže, Željka; Radoš, Milan; Krbot Skorić, Magdalena; Mrak, Goran; Nemir, Jakob; Milošević, Milan; Hajnšek, Sanja

Citirajte ovaj rad

Bujan Kovač, A., Petelin Gadže, Ž., Radoš, M., Krbot Skorić, M., Mrak, G., Nemir, J. ... Hajnšek, S. (2021). Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience. Clinical Neurology and Neurosurgery, 201.. doi: 10.1016/j.clineuro.2020.106426

Bujan Kovač, Andreja, et al. "Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience." Clinical Neurology and Neurosurgery, vol. 201, 2021. https://doi.org/10.1016/j.clineuro.2020.106426

Bujan Kovač, Andreja, Željka Petelin Gadže, Milan Radoš, Magdalena Krbot Skorić, Goran Mrak, Jakob Nemir, Milan Milošević i Sanja Hajnšek. "Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience." Clinical Neurology and Neurosurgery 201 (2021). https://doi.org/10.1016/j.clineuro.2020.106426

Bujan Kovač, A., et al. (2021) 'Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience', Clinical Neurology and Neurosurgery, 201. doi: 10.1016/j.clineuro.2020.106426

Bujan Kovač A, Petelin Gadže Ž, Radoš M, Krbot Skorić M, Mrak G, Nemir J, i sur.. Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience. Clinical Neurology and Neurosurgery [Internet]. 02.2021. [pristupljeno 23.12.2024.];201. doi: 10.1016/j.clineuro.2020.106426

A. Bujan Kovač, et al., "Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience", Clinical Neurology and Neurosurgery, vol. 201, Veljača 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:900886. [Citirano: 23.12.2024.]

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Podaci o radu
Naslov (engleski)Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience
AutorAndreja Bujan Kovač
AutorŽeljka Petelin Gadže
AutorMilan Radoš
AutorMagdalena Krbot Skorić
AutorGoran Mrak
AutorJakob Nemir
AutorMilan Milošević
AutorSanja Hajnšek
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(HRVATSKI INSTITUT ZA ISTRAŽIVANJE MOZGA)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA KIRURGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA NEUROLOGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA ZDRAVSTVENU EKOLOGIJU, MEDICINU RADA I SPORTA)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Neurologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Neuroznanost
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Javno zdravstvo i zdravstvena zaštita
Medicina rada i športa
Sažetak (engleski)
Objective: This study aimed to determine the role of brain MRI post-processing method MAP07 (Morphometric Analysis Program) in detecting epileptogenic brain lesions in patients with pharmacoresistant epilepsy (PE). MAP07 is a sophisticated diagnostic program that offers several morphometric maps and facilitates the detection and localization of hippocampal sclerosis (HS), focal cortical dysplasias (FCD), and other types of cortical malformations, which could be undetected by conventional visual MRI analysis (CVA). ----- Methods: 120 patients aged > 16 years with PE have been recruited. 3 T MRI was performed according to epilepsy imaging protocol followed by image postprocessing with a fully automated MATLAB script, MAP07, by applying SPM5 algorithms. Statistical analysis was performed in IBM SPSS Statistics, version 25.0. ----- Results: Analysis in our patients showed a high sensitivity of MAP07 with low specificity and with a high proportion of false-positive patients. After MRI analysis, out of 120 patients, 32 were found to have no structural abnormalities by conventional visual analysis in whom after MAP07 in 5 patients structural lesions were found (in one HS, in one FCD, in two perinatal vascular lesions, and in one hippocampal hyperintensity). There was a quite high overall coincidence of the findings of MAP07 and MRI for the detection of FCD, HS, perinatal ischemia/chronic vascular lesions, heterotopias, and polymicrogyria (kappa coefficient above 0.700). ----- Conclusions: MAP07 analysis is a useful, additional, and automated method that may guide re-evaluation of MRI by highlighting suspicious cortical regions, as a complementary method to CVA, by enhancing the visualization of cortical malformations and lesions.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaClinical Neurology and Neurosurgery
Brojčani podacivol. 201, 106426
p-ISSN0303-8467
e-ISSN1872-6968
DOIhttps://doi.org/10.1016/j.clineuro.2020.106426
URN:NBNurn:nbn:hr:105:900886
Datum objave publikacije2021-02
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S0303846720307691
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Datum isteka embarga: 2022-03-01
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2021-07-27 07:41:59