Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies

Znanstveni rad - Izvorni znanstveni rad

• Autor: Domagoj Dlaka
• Autor: Marko Švaco
• Autor: Darko Chudy
• Autor: Bojan Jerbić
• Autor: Bojan Šekoranja
• Autor: Filip Šuligoj
• Autor: Josip Vidaković
• Autor: Fadi Almahariq
• Autor: Dominik Romić
• Autor: Marina Raguž
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet; (KATEDRA ZA KIRURGIJU)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti; Kirurgija

Sažetak (engleski)

Aims: To report the outcomes of robot-assisted brain biopsies performed using a novel RONNA G4 system. The system was developed by a research group from the Faculty of Mechanical Engineering and Naval Architecture and a team of neurosurgeons from Dubrava University Hospital, University of Zagreb School of Medicine.
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Methods: This prospective study included 49 biopsies analyzed during one year: 23 robotic frameless and 26 frame-based Leksell stereotactic biopsies. We analyzed the presenting symptoms, tumor range and location, postoperative complications, pathohistological diagnosis, diagnostic yield, as well as operation and hospitalization duration. The target point error was calculated to assess the accuracy of the RONNA system.
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Results: No postoperative mortality, morbidity, or infections were observed. In the frameless robotic biopsy group, only one pathohistological diagnosis was inconclusive. Therefore, the diagnostic yield was 95.6% (22/23), similar to that of the framebased Leksell stereotactic biopsy group (95.1% or 25/26). The average target point error in the frameless robotic biopsy group was 2.15±1.22 mm (range 0.39-5.85).
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Conclusion: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.

• Ključne riječi (engleski): Biopsy; Brain / diagnostic imaging; Brain Neoplasms*; Humans; Neuronavigation; Prospective Studies; Robotic Surgical Procedures*; Robotics*; Stereotaxic Techniques
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Croatian Medical Journal
• Brojčani podaci: vol. 62, br. 4, str. 318-327
• p-ISSN: 0353-9504
• e-ISSN: 1332-8166
• DOI: https://doi.org/10.3325/cmj.2021.62.318
• URN:NBN: urn:nbn:hr:105:648475
• Datum objave publikacije: 2021-08-31
• URL dokumenta: http://www.cmj.hr/2021/62/4/34472734.htm
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2021-09-21 07:29:42