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Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study
Patient Preference and Adherence, 15 (2021); 359-373. https://doi.org/10.2147/PPA.S289692
Taylor, Peter C; Ancuta, Codrina; Nagy, Orsolya; de la Vega, María C; Gordeev, Andrey; Janková, Radka; Kalyoncu, Umut; Lagunes-Galindo, Ivan; Morović-Vergles, Jadranka; Souza, Mariana Peixoto GU e Silva de; Rojkovich, Bernadette; Sidiropoulos, Prodromos; Kawakami, Atsushi

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Taylor, P. C., Ancuta, C., Nagy, O., de la Vega, M. C., Gordeev, A., Janková, R. ... Kawakami, A. (2021). Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study. Patient Preference and Adherence, 15., 359-373. doi: 10.2147/PPA.S289692

Taylor, Peter C, et al. "Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study." Patient Preference and Adherence, vol. 15, 2021, str. 359-373. https://doi.org/10.2147/PPA.S289692

Taylor, Peter C, Codrina Ancuta, Orsolya Nagy, María C de la Vega, Andrey Gordeev, Radka Janková, Umut Kalyoncu, et al. "Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study." Patient Preference and Adherence 15 (2021): 359-373. https://doi.org/10.2147/PPA.S289692

Taylor, P. C., et al. (2021) 'Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study', Patient Preference and Adherence, 15, str. 359-373. doi: 10.2147/PPA.S289692

Taylor PC, Ancuta C, Nagy O, de la Vega MC, Gordeev A, Janková R, i sur.. Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study. Patient Preference and Adherence [Internet]. 17.02.2021. [pristupljeno 19.12.2024.];15:359-373. doi: 10.2147/PPA.S289692

P. C. Taylor, et al., "Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study", Patient Preference and Adherence, vol. 15, str. 359-373, Veljača 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:338950. [Citirano: 19.12.2024.]

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Naslov (engleski)Treatment Satisfaction, Patient Preferences, and the Impact of Suboptimal Disease Control in a Large International Rheumatoid Arthritis Cohort: SENSE Study
AutorPeter C Taylor
AutorCodrina Ancuta
AutorOrsolya Nagy
AutorMaría C de la Vega
AutorAndrey Gordeev
AutorRadka Janková
AutorUmut Kalyoncu
AutorIvan Lagunes-Galindo
AutorJadranka Morović-Vergles
AutorMariana Peixoto GU e Silva de Souza
AutorBernadette Rojkovich
AutorProdromos Sidiropoulos
AutorAtsushi Kawakami
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Patients' needs and perspectives are important determinants of treatment success in rheumatoid arthritis (RA). Assessing patients' perspectives can help identify unmet needs and enhance the understanding of treatment benefits. ----- Objective: The SENSE study assessed the impact of inadequate response to disease-modifying antirheumatic drugs (DMARDs) on treatment satisfaction, disease outcomes, and patient perspectives related to RA disease management. ----- Methods: SENSE was a noninterventional, cross-sectional study conducted in 18 countries across Europe, Asia, and South America. Adult patients with poorly controlled RA of moderate/high disease activity were eligible. Patient satisfaction was assessed by the Treatment Satisfaction Questionnaire for Medication (TSQM v1.4). Treatment adherence, healthcare resource utilization (HRU), quality of life (QoL), work ability, digital health literacy (DHL), patient preference information, and treatment strategy were also assessed. ----- Results: A total of 1624 patients were included in the study: most were female (84.2%) and middle-aged, and mean disease duration was 10.5 years. Mean TSQM global satisfaction subscore was 60.9, with only 13.5% of patients reporting good treatment satisfaction (TSQM global ≥80). The strongest predictor of good treatment satisfaction was treatment with advanced therapies. Most patients (87.4%) reported good treatment adherence. In general, patients had impaired QoL and work ability, high HRU, and 67.4% had poor DHL. Leading treatment expectations were "general improvement of arthritis" and "less joint pain". Most patients preferred oral RA medications (60.7%) and rapid (≤1 week) onset of action (71.1%). "Increased risk for malignancies" and "increased risk for cardiovascular disease" were the least acceptable side effects. Despite suboptimal control, advanced therapies were only used in a minority of patients, and DMARD switches were planned for only half of the patients. ----- Conclusion: Suboptimal disease control negatively impacts treatment satisfaction, work ability, QoL, and HRU. Data collected on patient perspectives may inform shared decision-making and optimize treat-to-target strategies for improving patient outcomes in RA.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPatient Preference and Adherence
Brojčani podacivol. 15, str. 359-373
e-ISSN1177-889X
DOIhttps://doi.org/10.2147/PPA.S289692
URN:NBNurn:nbn:hr:105:338950
Datum objave publikacije2021-02-17
URL dokumentahttps://www.dovepress.com/treatment-satisfaction-patient-preferences-and-the-impact-of-suboptima-peer-reviewed-article-PPA
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 3.0 (CC BY-NC 3.0)
Datum i vrijeme pohrane2021-09-30 08:21:33