prikaz prve stranice dokumenta Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review
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Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review
Tropical Medicine and Infectious Disease, 6 (2021), 2; 88. https://doi.org/10.3390/tropicalmed6020088
Vilibić-Čavlek, Tatjana; Savić, Vladimir; Ferenc, Thomas; Mrzljak, Anna; Barbić, Ljubo; Bogdanić, Maja; Stevanović, Vladimir; Tabain, Irena; Ferenčak, Ivana; Židovec-Lepej, Snježana

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Vilibić Čavlek, T., Savić, V., Ferenc, T., Mrzljak, A., Barbić, Lj., Bogdanić, M. ... Židovec Lepej, S. (2021). Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review. Tropical Medicine and Infectious Disease, 6. (2). doi: 10.3390/tropicalmed6020088

Vilibić Čavlek, Tatjana, et al. "Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review." Tropical Medicine and Infectious Disease, vol. 6, br. 2, 2021. https://doi.org/10.3390/tropicalmed6020088

Vilibić Čavlek, Tatjana, Vladimir Savić, Thomas Ferenc, Anna Mrzljak, Ljubo Barbić, Maja Bogdanić, Vladimir Stevanović, Irena Tabain, Ivana Ferenčak i Snježana Židovec Lepej. "Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review." Tropical Medicine and Infectious Disease 6, br. 2 (2021). https://doi.org/10.3390/tropicalmed6020088

Vilibić Čavlek, T., et al. (2021) 'Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review', Tropical Medicine and Infectious Disease, 6(2). doi: 10.3390/tropicalmed6020088

Vilibić Čavlek T, Savić V, Ferenc T, Mrzljak A, Barbić Lj, Bogdanić M, i sur.. Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review. Tropical Medicine and Infectious Disease [Internet]. 25.05.2021. [pristupljeno 21.12.2024.];6(2). doi: 10.3390/tropicalmed6020088

T. Vilibić Čavlek, et al., "Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review", Tropical Medicine and Infectious Disease, vol. 6, br. 2, Svibanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:818110. [Citirano: 21.12.2024.]

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Podaci o radu
Naslov (engleski)Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review
AutorTatjana Vilibić-Čavlek
AutorVladimir Savić
AutorThomas Ferenc
AutorAnna Mrzljak
AutorLjubo Barbić
AutorMaja Bogdanić
AutorVladimir Stevanović
AutorIrena Tabain
AutorIvana Ferenčak
AutorSnježana Židovec-Lepej
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne zoonotic virus distributed worldwide. Since serologic assays are limited to several laboratories, the disease has been underreported, often making it difficult to determine incidence and seroprevalence rates. Although human clinical cases are rarely recorded, LCMV remains an important cause of meningitis in humans. In addition, a fatal donor-derived LCMV infection in several clusters of solid organ transplant recipients further highlighted a pathogenic potential and clinical significance of this virus. In the transplant populations, abnormalities of the central nervous system were also found, but were overshadowed by the systemic illness resembling the Lassa hemorrhagic fever. LCMV is also an emerging fetal teratogen. Hydrocephalus, periventricular calcifications and chorioretinitis are the predominant characteristics of congenital LCMV infection, occurring in 87.5% of cases. Mortality in congenitally infected children is about 35%, while 70% of them show long-term neurologic sequelae. Clinicians should be aware of the risks posed by LCMV and should consider the virus in the differential diagnosis of aseptic meningitis, especially in patients who reported contact with rodents. Furthermore, LCMV should be considered in infants and children with unexplained hydrocephalus, intracerebral calcifications and chorioretinitis. Despite intensive interdisciplinary research efforts, efficient antiviral therapy for LCMV infection is still not available.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaTropical Medicine and Infectious Disease
Brojčani podacivol. 6, br. 2, 88
e-ISSN2414-6366
DOIhttps://doi.org/10.3390/tropicalmed6020088
URN:NBNurn:nbn:hr:105:818110
Datum objave publikacije2021-05-25
URL dokumentahttps://www.mdpi.com/2414-6366/6/2/88
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-11-04 09:07:41