prikaz prve stranice dokumenta Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease
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Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease
Frontiers in Immunology, 12 (2021); 676756. https://doi.org/10.3389/fimmu.2021.676756
Lelas, Antonela; Greinix, Hildegard Theresia; Wolff, Daniel; Eissner, Günther; Pavletić, Steven Živko; Pulanić, Dražen

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Lelas, A., Greinix, H. T., Wolff, D., Eissner, G., Pavletić, S. Ž. i Pulanić, D. (2021). Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease. Frontiers in Immunology, 12.. doi: 10.3389/fimmu.2021.676756

Lelas, Antonela, et al. "Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease." Frontiers in Immunology, vol. 12, 2021. https://doi.org/10.3389/fimmu.2021.676756

Lelas, Antonela, Hildegard Theresia Greinix, Daniel Wolff, Günther Eissner, Steven Živko Pavletić i Dražen Pulanić. "Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease." Frontiers in Immunology 12 (2021). https://doi.org/10.3389/fimmu.2021.676756

Lelas, A., et al. (2021) 'Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease', Frontiers in Immunology, 12. doi: 10.3389/fimmu.2021.676756

Lelas A, Greinix HT, Wolff D, Eissner G, Pavletić SŽ, Pulanić D. Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease. Frontiers in Immunology [Internet]. 30.04.2021. [pristupljeno 29.11.2024.];12. doi: 10.3389/fimmu.2021.676756

A. Lelas, H. T. Greinix, D. Wolff, G. Eissner, S. Ž. Pavletić i D. Pulanić, "Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease", Frontiers in Immunology, vol. 12, Travanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:528505. [Citirano: 29.11.2024.]

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Naslov (engleski)Von Willebrand Factor, Factor VIII, and Other Acute Phase Reactants as Biomarkers of Inflammation and Endothelial Dysfunction in Chronic Graft-Versus-Host Disease
AutorAntonela Lelas
AutorHildegard Theresia Greinix
AutorDaniel Wolff
AutorGünther Eissner
AutorSteven Živko Pavletić
AutorDražen Pulanić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Chronic graft-versus-host disease (cGvHD) is an immune mediated late complication of allogeneic hematopoietic stem cell transplantation (alloHSCT). Discovery of adequate biomarkers could identify high-risk patients and provide an effective pre-emptive intervention or early modification of therapeutic strategy, thus reducing prevalence and severity of the disease among long-term survivors of alloHSCT. Inflammation, endothelial injury, and endothelial dysfunction are involved in cGvHD development. Altered levels of acute phase reactants have shown a strong correlation with the activity of several immune mediated disorders and are routinely used in clinical practice. Since elevated von Willebrand factor (VWF) and factor VIII (FVIII) levels have been described as acute phase reactants that may indicate endothelial dysfunction and inflammation in different settings, including chronic autoimmune diseases, they could serve as potential candidate biomarkers of cGvHD. In this review we focused on reported data regarding VWF and FVIII as well as other markers of inflammation and endothelial dysfunction, evaluating their potential role in cGvHD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaFrontiers in Immunology
Brojčani podacivol. 12, 676756
e-ISSN1664-3224
DOIhttps://doi.org/10.3389/fimmu.2021.676756
URN:NBNurn:nbn:hr:105:528505
Datum objave publikacije2021-04-30
URL dokumentahttps://www.frontiersin.org/articles/10.3389/fimmu.2021.676756/full
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-11-04 09:31:21