prikaz prve stranice dokumenta Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease
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Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease
Gut, 71 (2022), 2; 402-414. https://doi.org/10.1136/gutjnl-2020-323419
Trebicka, Jonel; Gu, Wenyi; de Ledinghen, Victor; Aubé, Christophe; Krag, Aleksander; Praktiknjo, Michael; Castera, Laurent; Dumortier, Jerome; Bauer, David Josef Maria; Friedrich-Rust, Mireen; Pol, Stanislas; Grgurević, Ivica; Zheng, Rongqin; Francque, Sven; Gottfriedovà, Halima; Mustapić, Sanda; Sporea, Ioan; Berzigotti, Annalisa; Uschner, Frank Erhard; Simbrunner, Benedikt; Ronot, Maxime; Cassinotto, Christophe; Kjaergaard, Maria; Andrade, Filipe; Schulz, Martin; Semmler, Georg; Tješić Drinković, Ida; Chang, Johannes; Brol, Maximilian Joseph; Rautou, Pierre Emmanuel; Vanwolleghem, Thomas; Strassburg, Christian P; Boursier, Jerome; Ferstl, Philip Georg; Rasmussen, Ditlev Nytoft; Reiberger, Thomas; Vilgrain, Valerie; Guibal, Aymeric; Guillaud, Olivier; Zeuzem, Stefan; Vassord, Camille; Lu, Xue; Vonghia, Luisa; Senkerikova, Renata; Popescu, Alina; Margini, Cristina; Wang, Wenping; Thiele, Maja; Jansen, Chrisitan Više autora...

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Trebicka, J., Gu, W., de Ledinghen, V., Aubé, C., Krag, A., Praktiknjo, M. ... Jansen, C. (2022). Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease. Gut, 71. (2), 402-414. doi: 10.1136/gutjnl-2020-323419

Trebicka, Jonel, et al. "Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease." Gut, vol. 71, br. 2, 2022, str. 402-414. https://doi.org/10.1136/gutjnl-2020-323419

Trebicka, Jonel, Wenyi Gu, Victor de Ledinghen, Christophe Aubé, Aleksander Krag, Michael Praktiknjo, Laurent Castera, et al. "Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease." Gut 71, br. 2 (2022): 402-414. https://doi.org/10.1136/gutjnl-2020-323419

Trebicka, J., et al. (2022) 'Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease', Gut, 71(2), str. 402-414. doi: 10.1136/gutjnl-2020-323419

Trebicka J, Gu W, de Ledinghen V, Aubé C, Krag A, Praktiknjo M, i sur.. Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease. Gut [Internet]. 02.2022. [pristupljeno 19.04.2024.];71(2):402-414. doi: 10.1136/gutjnl-2020-323419

J. Trebicka, et al., "Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease", Gut, vol. 71, br. 2, str. 402-414, Veljača 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:485163. [Citirano: 19.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:485163
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Naslov (engleski)Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease
AutorJonel Trebicka
AutorWenyi Gu
AutorVictor de Ledinghen
AutorChristophe Aubé
AutorAleksander Krag
AutorMichael Praktiknjo
AutorLaurent Castera
AutorJerome Dumortier
AutorDavid Josef Maria Bauer
AutorMireen Friedrich-Rust
AutorStanislas Pol
AutorIvica Grgurević
AutorRongqin Zheng
AutorSven Francque
AutorHalima Gottfriedovà
AutorSanda Mustapić
AutorIoan Sporea
AutorAnnalisa Berzigotti
AutorFrank Erhard Uschner
AutorBenedikt Simbrunner
AutorMaxime Ronot
AutorChristophe Cassinotto
AutorMaria Kjaergaard
AutorFilipe Andrade
AutorMartin Schulz
AutorGeorg Semmler
AutorIda Tješić Drinković
AutorJohannes Chang
AutorMaximilian Joseph Brol
AutorPierre Emmanuel Rautou
AutorThomas Vanwolleghem
AutorChristian P Strassburg
AutorJerome Boursier
AutorPhilip Georg Ferstl
AutorDitlev Nytoft Rasmussen
AutorThomas Reiberger
AutorValerie Vilgrain
AutorAymeric Guibal
AutorOlivier Guillaud
AutorStefan Zeuzem
AutorCamille Vassord
AutorXue Lu
AutorLuisa Vonghia
AutorRenata Senkerikova
AutorAlina Popescu
AutorCristina Margini
AutorWenping Wang
AutorMaja Thiele
AutorChrisitan Jansen
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Objective: Liver stiffness measurement (LSM) is a tool used to screen for significant fibrosis and portal hypertension. The aim of this retrospective multicentre study was to develop an easy tool using LSM for clinical outcomes in advanced chronic liver disease (ACLD) patients. ----- Design: This international multicentre cohort study included a derivation ACLD patient cohort with valid two-dimensional shear wave elastography (2D-SWE) results. Clinical and laboratory parameters at baseline and during follow-up were recorded. LSM by transient elastography (TE) was also recorded if available. The primary outcome was overall mortality. The secondary outcome was the development of first/further decompensation. ----- Results: After screening 2148 patients (16 centres), 1827 patients (55 years, 62.4% men) were included in the 2D-SWE cohort, with median liver SWE (L-SWE) 11.8 kPa and a model for end stage liver disease (MELD) score of 8. Combination of MELD score and L-SWE predict independently of mortality (AUC 0.8). L-SWE cut-off at ≥20 kPa combined with MELD ≥10 could stratify the risk of mortality and first/further decompensation in ACLD patients. The 2-year mortality and decompensation rates were 36.9% and 61.8%, respectively, in the 305 (18.3%) high-risk patients (with L-SWE ≥20 kPa and MELD ≥10), while in the 944 (56.6%) low-risk patients, these were 1.1% and 3.5%, respectively. Importantly, this M10LS20 algorithm was validated by TE-based LSM and in an additional cohort of 119 patients with valid point shear SWE-LSM. ----- Conclusion: The M10LS20 algorithm allows risk stratification of patients with ACLD. Patients with L-SWE ≥20 kPa and MELD ≥10 should be followed closely and receive intensified care, while patients with low risk may be managed at longer intervals.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaGut
Brojčani podacivol. 71, br. 2, str. 402-414
p-ISSN0017-5749
e-ISSN1468-3288
DOIhttps://doi.org/10.1136/gutjnl-2020-323419
URN:NBNurn:nbn:hr:105:485163
Datum objave publikacije2022-02
URL dokumentahttps://gut.bmj.com/lookup/doi/10.1136/gutjnl-2020-323419
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2022-02-08 08:28:20