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FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19
Journal of Clinical Medicine, 10 (2021), 19; 4355. https://doi.org/10.3390/jcm10194355
Zelenika, Marko; Lucijanić, Marko; Bokun, Tomislav; Božin, Tonči; Barišić Jaman, Mislav; Tješić Drinković, Ida; Paštrović, Frane; Madir, Anita; Lukšić, Ivica; Piskač Živković, Nevenka; Luetić, Krešimir; Krznarić, Željko; Ostojić, Rajko; Filipec Kanižaj, Tajana; Bogadi, Ivan; Virović Jukić, Lucija; Kukla, Michal; Grgurević, Ivica Više autora...

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Zelenika, M., Lucijanić, M., Bokun, T., Božin, T., Barišić Jaman, M., Tješić Drinković, I. ... Grgurević, I. (2021). FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19. Journal of Clinical Medicine, 10. (19). doi: 10.3390/jcm10194355

Zelenika, Marko, et al. "FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19." Journal of Clinical Medicine, vol. 10, br. 19, 2021. https://doi.org/10.3390/jcm10194355

Zelenika, Marko, Marko Lucijanić, Tomislav Bokun, Tonči Božin, Mislav Barišić Jaman, Ida Tješić Drinković, Frane Paštrović, et al. "FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19." Journal of Clinical Medicine 10, br. 19 (2021). https://doi.org/10.3390/jcm10194355

Zelenika, M., et al. (2021) 'FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19', Journal of Clinical Medicine, 10(19). doi: 10.3390/jcm10194355

Zelenika M, Lucijanić M, Bokun T, Božin T, Barišić Jaman M, Tješić Drinković I, i sur.. FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19. Journal of Clinical Medicine [Internet]. 24.09.2021. [pristupljeno 03.12.2024.];10(19). doi: 10.3390/jcm10194355

M. Zelenika, et al., "FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19", Journal of Clinical Medicine, vol. 10, br. 19, Rujan 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:787917. [Citirano: 03.12.2024.]

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Naslov (engleski)FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19
AutorMarko Zelenika
AutorMarko Lucijanić
AutorTomislav Bokun
AutorTonči Božin
AutorMislav Barišić Jaman
AutorIda Tješić Drinković
AutorFrane Paštrović
AutorAnita Madir
AutorIvica Lukšić
AutorNevenka Piskač Živković
AutorKrešimir Luetić
AutorŽeljko Krznarić
MBZ: 75865
AutorRajko Ostojić
AutorTajana Filipec Kanižaj
AutorIvan Bogadi
AutorLucija Virović Jukić
AutorMichal Kukla
AutorIvica Grgurević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MAKSILOFACIJALNU KIRURGIJU SA STOMATOLOGIJOM)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Sažetak (engleski)
Background: Liver involvement in Coronavirus disease 2019 (COVID-19) has been recognised. We aimed to investigate the correlation of non-invasive surrogates of liver steatosis, fibrosis and inflammation using transient elastography (TE) and FibroScan-AST (FAST) score with (a) clinical severity and (b) 30-day composite outcome of mechanical ventilation (MV) or death among patients hospitalized due to COVID-19. ----- Method: Patients with non-critical COVID-19 at admission were included. Liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) were assessed by TE. Clinical severity of COVID-19 was assessed by 4C Mortality Score (4CMS) and need for high-flow nasal cannula (HFNC) oxygen supplementation. -----nResults: 217 patients were included (66.5% males, median age 65 years, 4.6% with history of chronic liver disease). Twenty-four (11.1%) patients met the 30-day composite outcome. Median LSM, CAP and FAST score were 5.2 kPa, 274 dB/m and 0.31, respectively, and neither was associated with clinical severity of COVID-19 at admission. In multivariate analysis FAST > 0.36 (OR 3.19, p = 0.036), 4CMS (OR 1.68, p = 0.002) and HFNC (OR 7.03, p = 0.001) were independent predictors of adverse composite outcome. ----- Conclusion: Whereas LSM and CAP failed to show correlation with COVID-19 severity and outcomes, FAST score was an independent risk factor for 30-day mortality or need for MV.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 10, br. 19, 4355
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm10194355
URN:NBNurn:nbn:hr:105:787917
Datum objave publikacije2021-09-24
URL dokumentahttps://www.mdpi.com/2077-0383/10/19/4355
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-04-07 09:47:42