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Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19
Clinical Transplantation, 35 (2021), 12; e14486. https://doi.org/10.1111/ctr.14486
Bašić‐Jukić, Nikolina; Ćorić, Marijana; Bulimbašić, Stela; Dika, Živka; Jurić, Ivana; Furić‐Čunko, Vesna; Katalinić, Lea; Kos, Jelena; Fištrek, Margareta; Kaštelan, Željko; Jelaković, Bojan

Citirajte ovaj rad

Bašić‐Jukić, N., Ćorić, M., Bulimbašić, S., Dika, Ž., Jurić, I., Furić‐Čunko, V. ... Jelaković, B. (2021). Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19. Clinical Transplantation, 35. (12). doi: 10.1111/ctr.14486

Bašić‐Jukić, Nikolina, et al. "Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19." Clinical Transplantation, vol. 35, br. 12, 2021. https://doi.org/10.1111/ctr.14486

Bašić‐Jukić, Nikolina, Marijana Ćorić, Stela Bulimbašić, Živka Dika, Ivana Jurić, Vesna Furić‐Čunko, Lea Katalinić, et al. "Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19." Clinical Transplantation 35, br. 12 (2021). https://doi.org/10.1111/ctr.14486

Bašić‐Jukić, N., et al. (2021) 'Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19', Clinical Transplantation, 35(12). doi: 10.1111/ctr.14486

Bašić‐Jukić N, Ćorić M, Bulimbašić S, Dika Ž, Jurić I, Furić‐Čunko V, i sur.. Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19. Clinical Transplantation [Internet]. 12.2021. [pristupljeno 16.04.2024.];35(12). doi: 10.1111/ctr.14486

N. Bašić‐Jukić, et al., "Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19", Clinical Transplantation, vol. 35, br. 12, Prosinac 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:047895. [Citirano: 16.04.2024.]

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Naslov (engleski)Histopathologic findings on indication renal allograft biopsies after recovery from acute COVID‐19
AutorNikolina Bašić‐Jukić
AutorMarijana Ćorić
AutorStela Bulimbašić
AutorŽivka Dika
AutorIvana Jurić
AutorVesna Furić‐Čunko
AutorLea Katalinić
AutorJelena Kos
AutorMargareta Fištrek
AutorŽeljko Kaštelan
AutorBojan Jelaković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA PATOLOGIJU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA UROLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Patologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Urologija
Sažetak (engleski)
Current knowledge on histopathological changes occurring after COVID-19 in transplanted kidneys is limited. Herein, we present renal allograft pathology findings in patients recovered from COVID-19. Six patients underwent indication biopsy, and one required allograft nephrectomy after acute COVID-19. Demographic data, clinical characteristics, and laboratory findings were recorded. The histopathological analysis included light microscopy, immunostaining, and electron microscopy. Five patients were hospitalized for acute COVID-19, and all were diagnosed with imaging-confirmed pneumonia, one requiring mechanical ventilation, and two requiring dialysis. Two patients had mild form. Histopathologic examination of renal allograft specimens revealed collapsing, perihilar, tip-lesion and secondary FSGS in one patient each. One patient had borderline acute cellular rejection, and two had chronic antibody-mediated rejection. Histopathologic changes of glomerular tufts were accompanied by acute tubular injury in four patients. None of our patients had signs of viral inclusions in kidney cells. One patient died and one remained dialysis-dependent after the good initial response to treatment. Patients with collapsing and perihilar FSGS had further progression of their chronic allograft nephropathy still without need for dialysis. In conclusion, diverse kidney pathology may be found in SARS-CoV-2-infected renal transplant patients. It seems that viral infection may affect the immune system with triggering of glomerular diseases, while the acute tubular injury is of multifactorial etiology. Direct viral effect is less likely.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaClinical Transplantation
Brojčani podacivol. 35, br. 12, e14486
p-ISSN0902-0063
e-ISSN1399-0012
DOIhttps://doi.org/10.1111/ctr.14486
URN:NBNurn:nbn:hr:105:047895
Datum objave publikacije2021-12
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/ctr.14486
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-04-28 07:46:24