prikaz prve stranice dokumenta The role of thyroid hormones in carotid arterial wall remodeling in women
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The role of thyroid hormones in carotid arterial wall remodeling in women
Romanian Journal of Internal Medicine, 60 (2022), 1; 24-33. https://doi.org/10.2478/rjim-2021-0028
Seferović Sarić, Maida; Jurašić, Miljenka-Jelena; Budinčević, Hrvoje; Milošević, Milan; Kranjčec, Bojana; Kovačić, Sanja; Leskovar, Jana; Demarin, Vida

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Seferović Sarić, M., Jurašić, M. J., Budinčević, H., Milošević, M., Kranjčec, B., Kovačić, S. ... Demarin, V. (2022). The role of thyroid hormones in carotid arterial wall remodeling in women. Romanian Journal of Internal Medicine, 60. (1), 24-33. doi: 10.2478/rjim-2021-0028

Seferović Sarić, Maida, et al. "The role of thyroid hormones in carotid arterial wall remodeling in women." Romanian Journal of Internal Medicine, vol. 60, br. 1, 2022, str. 24-33. https://doi.org/10.2478/rjim-2021-0028

Seferović Sarić, Maida, Miljenka Jelena Jurašić, Hrvoje Budinčević, Milan Milošević, Bojana Kranjčec, Sanja Kovačić, Jana Leskovar i Vida Demarin. "The role of thyroid hormones in carotid arterial wall remodeling in women." Romanian Journal of Internal Medicine 60, br. 1 (2022): 24-33. https://doi.org/10.2478/rjim-2021-0028

Seferović Sarić, M., et al. (2022) 'The role of thyroid hormones in carotid arterial wall remodeling in women', Romanian Journal of Internal Medicine, 60(1), str. 24-33. doi: 10.2478/rjim-2021-0028

Seferović Sarić M, Jurašić MJ, Budinčević H, Milošević M, Kranjčec B, Kovačić S, i sur.. The role of thyroid hormones in carotid arterial wall remodeling in women. Romanian Journal of Internal Medicine [Internet]. 17.03.2022. [pristupljeno 23.12.2024.];60(1):24-33. doi: 10.2478/rjim-2021-0028

M. Seferović Sarić, et al., "The role of thyroid hormones in carotid arterial wall remodeling in women", Romanian Journal of Internal Medicine, vol. 60, br. 1, str. 24-33, Ožujak 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:870022. [Citirano: 23.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:870022
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Naslov (engleski)The role of thyroid hormones in carotid arterial wall remodeling in women
AutorMaida Seferović Sarić
AutorMiljenka-Jelena Jurašić
AutorHrvoje Budinčević
AutorMilan Milošević
AutorBojana Kranjčec
AutorSanja Kovačić
AutorJana Leskovar
AutorVida Demarin
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA ZDRAVSTVENU EKOLOGIJU, MEDICINU RADA I SPORTA)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Javno zdravstvo i zdravstvena zaštita
Zdravstvena ekologija
Sažetak (engleski)
Introduction: Thyroid hormones affect the cardiovascular system, but the precise mechanisms of their effects on the development of atherosclerosis are not entirely clear. The relationship between subclinical hypothyroidism, dyslipidemia and carotid atherosclerosis has been widely investigated, but the findings were controversial. The aim of the present study was to determine whether female subjects with subclinical hypothyroidism (SHypo) have increased carotid intima-media thickness (IMT) compared with euthyroid subjects, as well as to examine the association of SHypo, carotid atherosclerosis and dyslipidemia. ----- Methods: This research included 100 women aged 30 to 70 years who were divided into two groups: the SHypo group including subjects with signs of subclinical hypothyroidism and the control group of euthyroid subjects. Carotid IMT thickness using B mode ultrasound was determined and its correlation with serum concentrations of fT4, TSH, CRP, and lipid profile including small dense LDL (sdLDL) was analysed. ----- Results: Subjects with SHypo had significantly increased carotid IMT (IMT ≥ 75th centile) in all three measured segments of the right (p <0.001) and the left (p = 0.001) carotid artery compared to the control group, with a significantly more frequent appearance of plaque (25% vs. 9%; p = 0.05). Significant positive correlations were found between higher TSH and higher IMT values. Increased age, LDL cholesterol, and TSH predicted thickening of the carotid artery IMT. ----- Conclusions: It is important to screen people showing early, subclinical signs of thyroid gland dysfunction due to its impact on carotid atherosclerosis development.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaRomanian Journal of Internal Medicine
Brojčani podacivol. 60, br. 1, str. 24-33
e-ISSN2501-062X
DOIhttps://doi.org/10.2478/rjim-2021-0028
URN:NBNurn:nbn:hr:105:870022
Datum objave publikacije2022-03-17
URL dokumentahttps://www.sciendo.com/article/10.2478/rjim-2021-0028
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2022-06-02 09:01:48