Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies

Štoković, Nikola; Ivanjko, Natalia; Matičić, Dražen; Luyten, Frank P.; Vukičević, Slobodan

doi:10.3390/ma14133513

prikaz prve stranice dokumenta Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies

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Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies

Materials, 14 (2021), 13; 3513. https://doi.org/10.3390/ma14133513

Štoković, Nikola; Ivanjko, Natalia; Matičić, Dražen; Luyten, Frank P.; Vukičević, Slobodan

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APA 6th Edition

Štoković, N., Ivanjko, N., Matičić, D., Luyten, F. P. i Vukičević, S. (2021). Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies. Materials, 14. (13). doi: 10.3390/ma14133513

MLA 8th Edition

Štoković, Nikola, et al. "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies." Materials, vol. 14, br. 13, 2021. https://doi.org/10.3390/ma14133513

Chicago 17th Edition

Štoković, Nikola, Natalia Ivanjko, Dražen Matičić, Frank P. Luyten i Slobodan Vukičević. "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies." Materials 14, br. 13 (2021). https://doi.org/10.3390/ma14133513

Harvard

Štoković, N., et al. (2021) 'Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies', Materials, 14(13). doi: 10.3390/ma14133513

Vancouver

Štoković N, Ivanjko N, Matičić D, Luyten FP, Vukičević S. Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies. Materials [Internet]. 24.06.2021. [pristupljeno 13.11.2024.];14(13). doi: 10.3390/ma14133513

IEEE

N. Štoković, N. Ivanjko, D. Matičić, F. P. Luyten i S. Vukičević, "Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies", Materials, vol. 14, br. 13, Lipanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:423123. [Citirano: 13.11.2024.]

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Naslov (engleski)	Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
Autor	Nikola Štoković
Autor	Natalia Ivanjko
Autor	Dražen Matičić
Autor	Frank P. Luyten
Autor	Slobodan Vukičević
Autorova ustanova	Sveučilište u Zagrebu Medicinski fakultet (KATEDRA ZA ANATOMIJU)
Znanstveno / umjetničko područje, polje i grana	BIOMEDICINA I ZDRAVSTVO Temeljne medicinske znanosti Anatomija
Sažetak (engleski)	Bone morphogenetic proteins (BMPs) possess a unique ability to induce new bone formation. Numerous preclinical studies have been conducted to develop novel, BMP-based osteoinductive devices for the management of segmental bone defects and posterolateral spinal fusion (PLF). In these studies, BMPs were combined with a broad range of carriers (natural and synthetic polymers, inorganic materials, and their combinations) and tested in various models in mice, rats, rabbits, dogs, sheep, and non-human primates. In this review, we summarized bone regeneration strategies and animal models used for the initial, intermediate, and advanced evaluation of promising therapeutical solutions for new bone formation and repair. Moreover, in this review, we discuss basic aspects to be considered when planning animal experiments, including anatomical characteristics of the species used, appropriate BMP dosing, duration of the observation period, and sample size.
Ključne riječi (engleski)
Jezik	engleski
Vrsta publikacije	Znanstveni rad - Pregledni rad
Status objave	Objavljen
Vrsta recenzije	Recenziran
Verzija publikacije	Objavljena verzija rada (izdavačev PDF)
Naslov časopisa	Materials
Brojčani podaci	vol. 14, br. 13, 3513
e-ISSN	1996-1944
DOI	https://doi.org/10.3390/ma14133513
URN:NBN	urn:nbn:hr:105:423123
Datum objave publikacije	2021-06-24
Projekt	Šifra: KK.01.1.1.01.0008 Naziv (hrvatski): Znanstveni centar izvrsnosti za reproduktivnu i regenerativnu medicinu – istraživanja novih platformi i potencijala Voditelj: Slobodan Vukičević Pravna nadležnost: eu Financijer: EK
URL dokumenta	https://www.mdpi.com/1996-1944/14/13/3513
Vrsta resursa	Tekst
Prava pristupa	Otvoreni pristup
Uvjeti korištenja
Datum i vrijeme pohrane	2022-06-15 11:11:01