prikaz prve stranice dokumenta Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients
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Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients
Journal of Cardiac Surgery, 37 (2022), 4; 747-759. https://doi.org/10.1111/jocs.16253
Sef, Davorin; Verzelloni Sef, Alessandra; Trkulja, Vladimir; Raj, Binu; Lees, Nicholas J.; Walker, Christopher; Mitchell, Jerry; Petrou, Mario; De Robertis, Fabio; Stock, Ulrich; McGovern, Ian

Citirajte ovaj rad

Sef, D., Verzelloni Sef, A., Trkulja, V., Raj, B., Lees, N. J., Walker, C. ... McGovern, I. (2022). Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients. Journal of Cardiac Surgery, 37. (4), 747-759. doi: 10.1111/jocs.16253

Sef, Davorin, et al. "Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients." Journal of Cardiac Surgery, vol. 37, br. 4, 2022, str. 747-759. https://doi.org/10.1111/jocs.16253

Sef, Davorin, Alessandra Verzelloni Sef, Vladimir Trkulja, Binu Raj, Nicholas J. Lees, Christopher Walker, Jerry Mitchell, et al. "Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients." Journal of Cardiac Surgery 37, br. 4 (2022): 747-759. https://doi.org/10.1111/jocs.16253

Sef, D., et al. (2022) 'Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients', Journal of Cardiac Surgery, 37(4), str. 747-759. doi: 10.1111/jocs.16253

Sef D, Verzelloni Sef A, Trkulja V, Raj B, Lees NJ, Walker C, i sur.. Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients. Journal of Cardiac Surgery [Internet]. 04.2022. [pristupljeno 13.05.2024.];37(4):747-759. doi: 10.1111/jocs.16253

D. Sef, et al., "Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients", Journal of Cardiac Surgery, vol. 37, br. 4, str. 747-759, Travanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:872095. [Citirano: 13.05.2024.]

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Naslov (engleski)Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients
AutorDavorin Sef
AutorAlessandra Verzelloni Sef
AutorVladimir Trkulja
AutorBinu Raj
AutorNicholas J. Lees
AutorChristopher Walker
AutorJerry Mitchell
AutorMario Petrou
AutorFabio De Robertis
AutorUlrich Stock
AutorIan McGovern
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA TEMELJNU I KLINIČKU FARMAKOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Sažetak (engleski)
Objectives: Venovenous extracorporeal membrane oxygenation (VV-ECMO) is increasingly being used in acutely deteriorating patients with end-stage lung disease as a bridge to transplantation (BTT). It can allow critically ill recipients to remain eligible for lung transplants (LTx) while reducing pretransplant deconditioning. We analyzed early- and midterm postoperative outcomes of patients on VV-ECMO as a BTT and the impact of preoperative VV-ECMO on posttransplant survival outcomes. ------ Methods: All consecutive LTx performed at our institution between January 2012 and December 2018 were analyzed. After matching, BTT patients were compared with nonbridged LTx recipients. ----- Results: Out of 297 transplanted patients, 21 (7.1%) were placed on VV-ECMO as a BTT. After matching, we observed similar 30-day mortality between BTT and non-BTT patients (4.6% vs. 6.6%, p = .083) despite a higher incidence of early postoperative complications (need for ECMO, delayed chest closure, and acute kidney injury). Furthermore, preoperative VV-ECMO did not appear associated with 30-day or 1-year mortality in both frequentist and Bayesian analysis (odds ratio [OR]: 0.35, 95% confidence interval: 0.03-3.49, p = .369; OR: 0.27, 95% credible interval: 0.01-3.82, p = 84.7%, respectively). In sensitivity analysis, both subgroups were similar in respect to 30-day (7.8% vs. 6.5%, p = .048) and 1-year mortality (12.5% vs. 18%, p = .154). ----- Conclusions: Patients with acute refractory respiratory failure while waiting for LTx represent a high-risk cohort of patients. VV-ECMO as a BTT is a reasonable strategy in adult patients with acceptable operative mortality and 1-year survival comparable to non-BTT patients.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaJournal of Cardiac Surgery
Brojčani podacivol. 37, br. 4, str. 747-759
p-ISSN0886-0440
e-ISSN1540-8191
DOIhttps://doi.org/10.1111/jocs.16253
URN:NBNurn:nbn:hr:105:872095
Datum objave publikacije2022-04
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/jocs.16253
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Datum isteka embarga: 2023-05-01
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-06-15 12:43:04