prikaz prve stranice dokumenta The role of statins in lung cancer
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The role of statins in lung cancer
Archives of Medical Science, 18 (2021), 1; 141-152. https://doi.org/10.5114/aoms/123225
Amin, Fatemeh; Fathi, Farzaneh; Reiner, Željko; Banach, Maciej; Sahebkar, Amirhossein

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Amin, F., Fathi, F., Reiner, Ž., Banach, M. i Sahebkar, A. (2021). The role of statins in lung cancer. Archives of Medical Science, 18. (1), 141-152. doi: 10.5114/aoms/123225

Amin, Fatemeh, et al. "The role of statins in lung cancer." Archives of Medical Science, vol. 18, br. 1, 2021, str. 141-152. https://doi.org/10.5114/aoms/123225

Amin, Fatemeh, Farzaneh Fathi, Željko Reiner, Maciej Banach i Amirhossein Sahebkar. "The role of statins in lung cancer." Archives of Medical Science 18, br. 1 (2021): 141-152. https://doi.org/10.5114/aoms/123225

Amin, F., et al. (2021) 'The role of statins in lung cancer', Archives of Medical Science, 18(1), str. 141-152. doi: 10.5114/aoms/123225

Amin F, Fathi F, Reiner Ž, Banach M, Sahebkar A. The role of statins in lung cancer. Archives of Medical Science [Internet]. 18.03.2021. [pristupljeno 09.05.2024.];18(1):141-152. doi: 10.5114/aoms/123225

F. Amin, F. Fathi, Ž. Reiner, M. Banach i A. Sahebkar, "The role of statins in lung cancer", Archives of Medical Science, vol. 18, br. 1, str. 141-152, Ožujak 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:167885. [Citirano: 09.05.2024.]

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Podaci o radu
Naslov (engleski)The role of statins in lung cancer
AutorFatemeh Amin
AutorFarzaneh Fathi
AutorŽeljko Reiner
AutorMaciej Banach
AutorAmirhossein Sahebkar
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Lung cancer is one of the most common causes of cancer-related mortality in the 21st century. Statins as inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase not only reduce the cholesterol levels in the blood and decrease the risk of cardiovascular disease but may also play an important role in the prevention and treatment of lung cancer. Statins have several antitumor properties including the ability to reduce cell proliferation and angiogenesis, decrease invasion and synergistic suppression of lung cancer progression. Statins induce tumor cell apoptosis by inhibition of downstream products such as small GTP-binding proteins, Rho, Ras and Rac, which are dependent on isoprenylation. Statins reduce angiogenesis in tumors by down-regulation of pro-angiogenic factors, such as vascular endothelial growth factor. In this review, the feasibility and efficacy of statins in the prevention and treatment of lung cancer are discussed.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaArchives of Medical Science
Brojčani podacivol. 18, br. 1, str. 141-152
p-ISSN1734-1922
e-ISSN1896-9151
DOIhttps://doi.org/10.5114/aoms/123225
URN:NBNurn:nbn:hr:105:167885
Datum objave publikacije2021-03-18
URL dokumentahttps://www.archivesofmedicalscience.com/The-role-of-statins-in-lung-cancer,123225,0,2.html
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Dijeli pod istim uvjetima 4.0 međunarodna (CC BY-NC-SA 4.0)
Datum i vrijeme pohrane2022-10-24 11:05:20